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ndufc2 NADH:ubiquinone oxidoreductase subunit C2 [ Danio rerio (zebrafish) ]

Gene ID: 541390, updated on 2-Nov-2024

Summary

Official Symbol
ndufc2provided by ZNC
Official Full Name
NADH:ubiquinone oxidoreductase subunit C2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050320-87
See related
Ensembl:ENSDARG00000102115 AllianceGenome:ZFIN:ZDB-GENE-050320-87
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110155
Summary
Predicted to act upstream of or within mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to several human genes including NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See ndufc2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (11427622..11443217)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (11505227..11520822)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene prolylcarboxypeptidase (angiotensinase C) Neighboring gene RAB30, member RAS oncogene family Neighboring gene uncharacterized LOC137487722 Neighboring gene uncharacterized LOC137487723

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 subunit C2
Names
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
NP_001013535.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013517.1NP_001013535.1  NADH dehydrogenase [ubiquinone] 1 subunit C2

    See identical proteins and their annotated locations for NP_001013535.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091447
    UniProtKB/TrEMBL
    Q5BJK4
    Related
    ENSDARP00000141007.1, ENSDART00000168688.2
    Conserved Domains (1) summary
    pfam06374
    Location:4110
    NDUF_C2; NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    11427622..11443217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)