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ppp1r13l protein phosphatase 1, regulatory subunit 13 like [ Danio rerio (zebrafish) ]

Gene ID: 541507, updated on 2-Nov-2024

Summary

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Official Symbol
ppp1r13lprovided by ZNC
Official Full Name
protein phosphatase 1, regulatory subunit 13 likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050327-33
See related
Ensembl:ENSDARG00000013777 AllianceGenome:ZFIN:ZDB-GENE-050327-33
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:113058
Summary
Predicted to be involved in positive regulation of cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Orthologous to human PPP1R13L (protein phosphatase 1 regulatory subunit 13 like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See ppp1r13l in Genome Data Viewer
Location:
chromosome: 18
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (35842934..35898821)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (35861922..35917877)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein U-like 1 Neighboring gene outer mitochondrial membrane lipid metabolism regulator OPA3 Neighboring gene uncharacterized LOC137488315 Neighboring gene transmembrane protein 91 Neighboring gene exosome component 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Modeling Sarcoglycanopathy in Danio rerio. Dalla Barba F, et al. Int J Mol Sci, 2023 Aug 11. PMID 37628888, Free PMC Article
  2. Phylogenetic and Expression Analysis of Fos Transcription Factors in Zebrafish. Kubra K, et al. Int J Mol Sci, 2022 Sep 3. PMID 36077499, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in positive regulation of cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
relA-associated inhibitor
Names
protein phosphatase 1, regulatory (inhibitor) subunit 13 like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014320.2 → NP_001014342.1  relA-associated inhibitor

    See identical proteins and their annotated locations for NP_001014342.1

    Status: PROVISIONAL

    Source sequence(s)
    BC091786
    UniProtKB/TrEMBL
    Q58ER8
    Related
    ENSDARP00000126054.1, ENSDART00000151587.3
    Conserved Domains (5) summary
    cd11952
    Location:720 → 774
    SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
    cd00204
    Location:594 → 689
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:564 → 649
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:621 → 672
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:585 → 616
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    35842934..35898821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005173644.5 → XP_005173701.1  relA-associated inhibitor isoform X1

    See identical proteins and their annotated locations for XP_005173701.1

    UniProtKB/TrEMBL
    A0A8M2BKW6, Q1L9A3
    Related
    ENSDARP00000106399.2, ENSDART00000131121.3
    Conserved Domains (5) summary
    cd11952
    Location:725 → 779
    SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
    cd00204
    Location:599 → 694
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:569 → 654
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:626 → 677
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:590 → 621
    ANK; ANK repeat [structural motif]

  2. XM_005173643.5 → XP_005173700.1  relA-associated inhibitor isoform X1

    See identical proteins and their annotated locations for XP_005173700.1

    UniProtKB/TrEMBL
    A0A8M2BKW6, Q1L9A3
    Conserved Domains (5) summary
    cd11952
    Location:725 → 779
    SH3_iASPP; Src Homology 3 (SH3) domain of Inhibitor of ASPP protein (iASPP)
    cd00204
    Location:599 → 694
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:569 → 654
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:626 → 677
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:590 → 621
    ANK; ANK repeat [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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