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ppp1r11 protein phosphatase 1, regulatory (inhibitor) subunit 11 [ Danio rerio (zebrafish) ]

Gene ID: 550290, updated on 28-Oct-2024

Summary

Official Symbol
ppp1r11provided by ZNC
Official Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 11provided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-99
See related
Ensembl:ENSDARG00000036063 AllianceGenome:ZFIN:ZDB-GENE-050417-99
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fj64e04; zgc:110245
Summary
Predicted to enable protein phosphatase 1 binding activity; protein serine/threonine phosphatase inhibitor activity; and ubiquitin protein ligase activity. Predicted to be involved in defense response to Gram-positive bacterium; negative regulation of cytokine production; and ubiquitin-dependent protein catabolic process. Predicted to be active in nucleus. Orthologous to human PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See ppp1r11 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (27448625..27453637)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (27864402..27869414)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase b Neighboring gene valyl-tRNA synthetase 2, mitochondrial Neighboring gene si:ch73-25f10.6 Neighboring gene si:ch211-152p11.8 Neighboring gene small nucleolar RNA SNORD52

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein phosphatase 1 binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin protein ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in defense response to Gram-positive bacterium ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of cytokine production ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in ubiquitin-dependent protein catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
E3 ubiquitin-protein ligase PPP1R11
Names
protein phosphatase 1 regulatory subunit 11
NP_001017627.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017627.1NP_001017627.1  E3 ubiquitin-protein ligase PPP1R11

    See identical proteins and their annotated locations for NP_001017627.1

    Status: PROVISIONAL

    Source sequence(s)
    BC092823
    UniProtKB/Swiss-Prot
    Q568K2
    UniProtKB/TrEMBL
    A3KQ01
    Related
    ENSDARP00000052351.4, ENSDART00000052352.5
    Conserved Domains (1) summary
    pfam07491
    Location:3284
    PPI_Ypi1; Protein phosphatase inhibitor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    27448625..27453637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)