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prrg4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) [ Danio rerio (zebrafish) ]

Gene ID: 550330, updated on 12-Oct-2024

Summary

Official Symbol
prrg4provided by ZNC
Official Full Name
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)provided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-112
See related
Ensembl:ENSDARG00000030753 AllianceGenome:ZFIN:ZDB-GENE-050417-112
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:110234
Summary
Predicted to enable calcium ion binding activity. Predicted to be located in extracellular region and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human PRRG4 (proline rich and Gla domain 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See prrg4 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (45661475..45674932)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (45669785..45678106)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108180032 Neighboring gene eukaryotic translation initiation factor 3, subunit M Neighboring gene glutamine and serine rich 1 Neighboring gene DEP domain containing 7, paralog a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in blood coagulation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
transmembrane gamma-carboxyglutamic acid protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017637.2NP_001017637.1  transmembrane gamma-carboxyglutamic acid protein 4 precursor

    See identical proteins and their annotated locations for NP_001017637.1

    Status: VALIDATED

    Source sequence(s)
    CU896647, EH538457
    UniProtKB/TrEMBL
    A0A8M1N535, Q568L1
    Related
    ENSDARP00000125700.1, ENSDART00000151351.3
    Conserved Domains (1) summary
    smart00069
    Location:3497
    GLA; Domain containing Gla (gamma-carboxyglutamate) residues

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    45661475..45674932
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068214766.1XP_068070867.1  transmembrane gamma-carboxyglutamic acid protein 4 isoform X1