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pdss1 prenyl (decaprenyl) diphosphate synthase, subunit 1 [ Danio rerio (zebrafish) ]

Gene ID: 550349, updated on 2-Nov-2024

Summary

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Official Symbol
pdss1provided by ZNC
Official Full Name
prenyl (decaprenyl) diphosphate synthase, subunit 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4430
See related
Ensembl:ENSDARG00000017910 AllianceGenome:ZFIN:ZDB-GENE-030131-4430
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tprt; wu:fc11f12; wu:fd05d05; zgc:112058
Summary
Predicted to enable prenyltransferase activity. Predicted to be involved in isoprenoid biosynthetic process and ubiquinone biosynthetic process. Predicted to be part of polyprenyl diphosphate synthase complex. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; lens placode; musculature system; optic vesicle; and segmental plate. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Orthologous to human PDSS1 (decaprenyl diphosphate synthase subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See pdss1 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (6015297..6024461, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (5985968..5995143, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA binding domain containing 5a Neighboring gene abl-interactor 1a Neighboring gene tripartite motif-containing protein 16-like Neighboring gene finTRIM family, member 61

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Rossmann MP, et al. Science, 2021 May 14. PMID 33986176, Free PMC Article
  2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables all-trans-decaprenyl-diphosphate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables prenyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in isoprenoid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in ubiquinone biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of polyprenyl diphosphate synthase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
all trans-polyprenyl-diphosphate synthase PDSS1
Names
trans-prenyltransferase
NP_001017656.1
XP_005162562.1
XP_021325838.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017656.1 → NP_001017656.1  all trans-polyprenyl-diphosphate synthase PDSS1

    See identical proteins and their annotated locations for NP_001017656.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093175
    UniProtKB/TrEMBL
    A0A8M1N5E6, Q567H1
    Related
    ENSDARP00000040864.5, ENSDART00000040865.6
    Conserved Domains (2) summary
    PLN02890
    Location:26 → 411
    PLN02890; geranyl diphosphate synthase
    cl00210
    Location:92 → 409
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    6015297..6024461 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005162505.4 → XP_005162562.1  all trans-polyprenyl-diphosphate synthase PDSS1 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B9D7
    Conserved Domains (2) summary
    PLN02890
    Location:26 → 410
    PLN02890; geranyl diphosphate synthase
    cl00210
    Location:92 → 408
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

  2. XM_021470163.2 → XP_021325838.1  all trans-polyprenyl-diphosphate synthase PDSS1 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PFZ8
    Conserved Domains (1) summary
    cl00210
    Location:57 → 374
    Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1
Nucleotide Protein Strain
Heading Accession and Version

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