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arf4b ADP-ribosylation factor 4b [ Danio rerio (zebrafish) ]

Gene ID: 550402, updated on 2-Nov-2024

Summary

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Official Symbol
arf4bprovided by ZNC
Official Full Name
ADP-ribosylation factor 4bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-205
See related
Ensembl:ENSDARG00000100339 AllianceGenome:ZFIN:ZDB-GENE-050417-205
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
arf4; zgc:112199
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. Predicted to act upstream of or within protein transport. Predicted to be located in Golgi apparatus. Is expressed in brain; eye; forebrain; and midbrain. Orthologous to human ARF4 (ADP ribosylation factor 4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See arf4b in Genome Data Viewer
Location:
chromosome: 11
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (42466577..42472501, complement)
105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003336639.1 (22141..23751, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene sarcolemma associated protein a Neighboring gene uncharacterized LOC137496736 Neighboring gene DENN/MADD domain containing 6Aa Neighboring gene si:ch1073-165f9.2 Neighboring gene zgc:110286

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Proteomics profiling of single organs from individual adult zebrafish. Abramsson A, et al. Zebrafish, 2010 Jun. PMID 20392139
  2. Zebrafish fat-free, a novel Arf effector, regulates phospholipase D to mediate lipid and glucose metabolism. Liu HY, et al. Biochim Biophys Acta, 2010 Dec. PMID 20816853
  3. Rgp1 contributes to craniofacial cartilage development and Rab8a-mediated collagen II secretion. Ritter DJ, et al. Front Endocrinol (Lausanne), 2023. PMID 36843607, Free PMC Article
  4. Generation and characterization of a novel gne Knockout Model in Zebrafish. Livne H, et al. Front Cell Dev Biol, 2022. PMID 36353515, Free PMC Article
  5. Examining the responses of the zebrafish (Danio rerio) gastrointestinal system to the suspected obesogen diethylhexyl phthalate. Buerger AN, et al. Environ Pollut, 2019 Feb. PMID 30682743

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ADP-ribosylation factor 4b
Names
ADP-ribosylation factor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017707.1 → NP_001017707.1  ADP-ribosylation factor 4b

    See identical proteins and their annotated locations for NP_001017707.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093261
    UniProtKB/TrEMBL
    Q566Z9
    Related
    ENSDARP00000130845.2, ENSDART00000166624.2
    Conserved Domains (2) summary
    smart00178
    Location:15 → 174
    SAR; Sar1p-like members of the Ras-family of small GTPases
    cl21455
    Location:1 → 180
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    42466577..42472501 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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