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hmgb3b high mobility group box 3b [ Danio rerio (zebrafish) ]

Gene ID: 550466, updated on 28-Oct-2024

Summary

Official Symbol
hmgb3bprovided by ZNC
Official Full Name
high mobility group box 3bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-290
See related
Ensembl:ENSDARG00000006408 AllianceGenome:ZFIN:ZDB-GENE-050417-290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hmgb3; fa19b06; fj43d02; wu:fa19b06; wu:fj43d02; zgc:112073
Summary
Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome and nucleus. Is expressed in central nervous system; intermediate cell mass of mesoderm; ovary; pectoral fin bud; and telencephalon. Human ortholog(s) of this gene implicated in syndromic microphthalmia 13. Orthologous to human HMGB3 (high mobility group box 3). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See hmgb3b in Genome Data Viewer
Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (34119789..34129776)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (34085299..34095286)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene zgc:110222 Neighboring gene myotubularin related protein 1b Neighboring gene transient receptor potential cation channel, subfamily C, member 5b Neighboring gene ALG13 UDP-N-acetylglucosaminyltransferase subunit

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding, bending IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
high mobility group protein B3b
Names
high-mobility group box 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017769.1NP_001017769.1  high mobility group protein B3b

    See identical proteins and their annotated locations for NP_001017769.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093186
    UniProtKB/TrEMBL
    Q567G0
    Related
    ENSDARP00000007566.6, ENSDART00000024750.8
    Conserved Domains (2) summary
    pfam00505
    Location:94161
    HMG_box; HMG (high mobility group) box
    pfam09011
    Location:778
    HMG_box_2; HMG-box domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    34119789..34129776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)