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cryba4 crystallin, beta A4 [ Danio rerio (zebrafish) ]

Gene ID: 553178, updated on 2-Nov-2024

Summary

Official Symbol
cryba4provided by ZNC
Official Full Name
crystallin, beta A4provided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-143
See related
Ensembl:ENSDARG00000024548 AllianceGenome:ZFIN:ZDB-GENE-050522-143
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:109979
Summary
Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in lens and solid lens vesicle. Human ortholog(s) of this gene implicated in cataract 23. Orthologous to human CRYBA4 (crystallin beta A4). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See cryba4 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (44042227..44051466)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (44195374..44204669)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase short chain Neighboring gene crystallin, beta B1 Neighboring gene G protein-coupled receptor kinase 3 Neighboring gene unconventional myosin-XVIIIb-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables structural constituent of eye lens IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in lens development in camera-type eye IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in visual perception IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001018125.1NP_001018135.1  beta-crystallin A4

    See identical proteins and their annotated locations for NP_001018135.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095102
    UniProtKB/TrEMBL
    A0A2R8QSC7, A0A8N7XJD7, F1R761, Q52JI7
    Related
    ENSDARP00000046171.7, ENSDART00000046172.9
    Conserved Domains (2) summary
    smart00247
    Location:106194
    XTALbg; Beta/gamma crystallins
    pfam00030
    Location:1397
    Crystall; Beta/Gamma crystallin

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    44042227..44051466
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009305688.4XP_009303963.1  beta-crystallin A4 isoform X1

    See identical proteins and their annotated locations for XP_009303963.1

    UniProtKB/TrEMBL
    A0A2R8QSC7, A0A8N7XJD7, F1R761, Q52JI7
    Related
    ENSDARP00000156225.1, ENSDART00000190006.1
    Conserved Domains (2) summary
    smart00247
    Location:106194
    XTALbg; Beta/gamma crystallins
    pfam00030
    Location:1397
    Crystall; Beta/Gamma crystallin