uggt1 UDP-glucose glycoprotein glucosyltransferase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: uggt1provided by ZNC
Official Full Name: UDP-glucose glycoprotein glucosyltransferase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-061103-619
See related: Ensembl:ENSDARG00000054746 AllianceGenome:ZFIN:ZDB-GENE-061103-619
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:152896
Summary: Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Predicted to be involved in ER-associated misfolded protein catabolic process and protein N-linked glycosylation via asparagine. Predicted to act upstream of or within protein glycosylation. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endoplasmic reticulum. Orthologous to human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 41

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	2	NC_007113.7 (40830810..40890076, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	2	NC_007113.6 (40976576..41035817, complement)

Chromosome 2 - NC_007113.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables UDP-glucose:glycoprotein glucosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-glucose:glycoprotein glucosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ERAD pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein N-linked glycosylation via asparagine	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum lumen	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-glucose:glycoprotein glucosyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077534.1 → NP_001071002.1 UDP-glucose:glycoprotein glucosyltransferase 1 precursor

See identical proteins and their annotated locations for NP_001071002.1

Status: PROVISIONAL

Source sequence(s)

BC125832

UniProtKB/TrEMBL

A0JMD3

Related

ENSDARP00000148534.1, ENSDART00000191746.1

Conserved Domains (2) summary

cd06432
Location:1226 → 1473

GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family

pfam06427
Location:22 → 1171

UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007113.7 Reference GRCz11 Primary Assembly

Range

40830810..40890076 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021480334.1 → XP_021336009.1 UDP-glucose:glycoprotein glucosyltransferase 1 isoform X1

UniProtKB/TrEMBL

A0A8M9QEQ5

Related

ENSDARP00000107250.3, ENSDART00000123886.3

Conserved Domains (2) summary

cd06432
Location:1263 → 1510

GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family

pfam06427
Location:51 → 1208

UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase
XM_021480338.1 → XP_021336013.1 UDP-glucose:glycoprotein glucosyltransferase 1 isoform X2

UniProtKB/TrEMBL

A0A8M9Q922

Conserved Domains (2) summary

cd06432
Location:1255 → 1502

GT8_HUGT1_C_like; The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family

pfam06427
Location:51 → 1200

UDP-g_GGTase; UDP-glucose:Glycoprotein Glucosyltransferase