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mis18a MIS18 kinetochore protein A [ Danio rerio (zebrafish) ]

Gene ID: 553502, updated on 28-Oct-2024

Summary

Official Symbol
mis18aprovided by ZNC
Official Full Name
MIS18 kinetochore protein Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-091204-314
See related
Ensembl:ENSDARG00000035333 AllianceGenome:ZFIN:ZDB-GENE-091204-314
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-189i22.1
Summary
Predicted to be involved in CENP-A containing chromatin assembly and chromosome segregation. Predicted to act upstream of or within cell division. Predicted to be located in chromatin. Predicted to be active in chromosome, centromeric region and nucleus. Orthologous to human MIS18A (MIS18 kinetochore protein A). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See mis18a in Genome Data Viewer
Location:
chromosome: 10
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (33588746..33594111)
105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (33643958..33650251)

Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene si:dkey-18a10.3 Neighboring gene cilia and flagella associated protein 298 Neighboring gene eva-1 homolog C (C. elegans) Neighboring gene hormonally up-regulated Neu-associated kinase Neighboring gene beta 3-glucosyltransferase b Neighboring gene uncharacterized LOC101886689

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in CENP-A containing chromatin assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in chromosome segregation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in chromatin IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in chromosome, centromeric region IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein Mis18-alpha
Names
MIS18 kinetochore protein homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007121.7 Reference GRCz11 Primary Assembly

    Range
    33588746..33594111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479407.2XP_021335082.1  protein Mis18-alpha

    UniProtKB/TrEMBL
    A0A8M9PYB8, F1RC19
    Related
    ENSDARP00000051197.5, ENSDART00000051198.6
    Conserved Domains (1) summary
    pfam03226
    Location:39137
    Yippee-Mis18; Yippee zinc-binding/DNA-binding /Mis18, centromere assembly

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394793.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    4657..10022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002663588.6XP_002663634.2  protein Mis18-alpha

    UniProtKB/TrEMBL
    A0A8M9PYB8, F1RC19
    Conserved Domains (1) summary
    pfam03226
    Location:39137
    Yippee-Mis18; Yippee zinc-binding/DNA-binding /Mis18, centromere assembly

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395291.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    4657..10022
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474214.2XP_021329889.1  protein Mis18-alpha

    UniProtKB/TrEMBL
    A0A8M9PYB8, F1RC19
    Conserved Domains (1) summary
    pfam03226
    Location:39137
    Yippee-Mis18; Yippee zinc-binding/DNA-binding /Mis18, centromere assembly