atp6v0a1b ATPase H+ transporting V0 subunit a1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: atp6v0a1bprovided by ZNC
Official Full Name: ATPase H+ transporting V0 subunit a1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-215
See related: Ensembl:ENSDARG00000015174 AllianceGenome:ZFIN:ZDB-GENE-050522-215
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fj37e01; zgc:112214
Summary: Predicted to enable ATPase binding activity. Acts upstream of or within cellular response to xenobiotic stimulus. Predicted to be located in clathrin-coated vesicle membrane; melanosome; and synaptic vesicle membrane. Predicted to be part of vacuolar proton-transporting V-type ATPase complex. Predicted to be active in plasma membrane. Is expressed in female organism. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 104. Orthologous to human ATP6V0A1 (ATPase H+ transporting V0 subunit a1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 24

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (7594105..7632105, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (7564786..7602822, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to xenobiotic stimulus	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in clathrin-coated vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in melanosome	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of proton-transporting V-type ATPase, V0 domain	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info
located_in synaptic vesicle membrane	IEA Inferred from Electronic Annotation more info
part_of vacuolar proton-transporting V-type ATPase, V0 domain	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: V-type proton ATPase 116 kDa subunit a isoform 1b; V-type proton ATPase 116 kDa subunit a

Names: ATPase, H+ transporting, lysosomal V0 subunit a; ATPase, H+ transporting, lysosomal V0 subunit a1b

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020666.1 → NP_001018502.1 V-type proton ATPase 116 kDa subunit a isoform 1b

See identical proteins and their annotated locations for NP_001018502.1

Status: PROVISIONAL

Source sequence(s)

BC095691

UniProtKB/TrEMBL

Q502H9

Related

ENSDARP00000041713.6, ENSDART00000041714.7

Conserved Domains (2) summary

COG1269
Location:27 → 831

NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]

pfam01496
Location:28 → 829

V_ATPase_I; V-type ATPase 116kDa subunit family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007135.7 Reference GRCz11 Primary Assembly

Range

7594105..7632105 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009297243.3 → XP_009295518.1 V-type proton ATPase 116 kDa subunit a isoform X1

UniProtKB/TrEMBL

A0A8M3AYX3

Conserved Domains (2) summary

COG1269
Location:27 → 860

NtpI; Archaeal/vacuolar-type H+-ATPase subunit I/STV1 [Energy production and conversion]

pfam01496
Location:28 → 858

V_ATPase_I; V-type ATPase 116kDa subunit family