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rgrb retinal G protein coupled receptor b [ Danio rerio (zebrafish) ]

Gene ID: 554142, updated on 28-Oct-2024

Summary

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Official Symbol
rgrbprovided by ZNC
Official Full Name
retinal G protein coupled receptor bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-447
See related
AllianceGenome:ZFIN:ZDB-GENE-050522-447
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rgr2; zgc:92677; wu:fb64c10; zgc:109930
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; phototransduction; and visual perception. Predicted to be located in membrane. Is expressed in several structures, including digestive system; endocrine system; optic vesicle; visual system; and yolk syncytial layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 44. Orthologous to human RGR (retinal G protein coupled receptor). [provided by Alliance of Genome Resources, Oct 2024]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Genomic context

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See rgrb in Genome Data Viewer
Location:
chromosome: 12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (48965034..48970458, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (48943505..48948929, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene calcium-activated potassium channel subunit alpha-1-like Neighboring gene potassium large conductance calcium-activated channel, subfamily M, alpha member 1b Neighboring gene solute carrier family 18 member 3b Neighboring gene cadherin-related family member 1a Neighboring gene leucine-rich repeat, immunoglobulin-like and transmembrane domains 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Transcriptional and Behavioral Responses of Zebrafish Larvae to Microcystin-LR Exposure. Tzima E, et al. Int J Mol Sci, 2017 Feb 9. PMID 28208772, Free PMC Article
  2. Silver nanoparticles affect lens rather than retina development in zebrafish embryos. Zhang Y, et al. Ecotoxicol Environ Saf, 2018 Nov 15. PMID 30056342
  3. Zebrafish Circadian Clock Entrainment and the Importance of Broad Spectral Light Sensitivity. Steindal IAF, et al. Front Physiol, 2020. PMID 32922310, Free PMC Article
  4. Analysis of opsin gene family of Crimson snapper (Lutjanus erythropterus). Liang Q, et al. Gene, 2022 Jan 10. PMID 34509581
  5. An extended family of novel vertebrate photopigments is widely expressed and displays a diversity of function. Davies WI, et al. Genome Res, 2015 Nov. PMID 26450929, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phototransduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within visual perception IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
retinal G protein coupled receptor b
Names
retinal pigment epithelium retinal G protein receptor-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024436.1 → NP_001019607.1  retinal G protein coupled receptor b

    See identical proteins and their annotated locations for NP_001019607.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095058
    UniProtKB/TrEMBL
    Q504E4, Q6DH22
    Conserved Domains (1) summary
    pfam00001
    Location:33 → 254
    7tm_1; 7 transmembrane receptor (rhodopsin family)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    48965034..48970458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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