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nbr1b NBR1 autophagy cargo receptor b [ Danio rerio (zebrafish) ]

Gene ID: 555713, updated on 2-Nov-2024

Summary

Official Symbol
nbr1bprovided by ZNC
Official Full Name
NBR1 autophagy cargo receptor bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-170215-1
See related
Ensembl:ENSDARG00000078772 AllianceGenome:ZFIN:ZDB-GENE-170215-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Orthologous to human NBR1 (NBR1 autophagy cargo receptor). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See nbr1b in Genome Data Viewer
Location:
chromosome: 3
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (32933721..32952043)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (32801978..32820329)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene glucose-6-phosphatase catalytic subunit 1b Neighboring gene amine oxidase copper containing 2 Neighboring gene caspase 6b.1, apoptosis-related cysteine peptidase Neighboring gene caspase 6, apoptosis-related cysteine peptidase a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General protein information

Preferred Names
next to BRCA1 gene 1 protein
Names
neighbor of BRCA1 gene 1
neighbor of brca1 gene 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001386643.1NP_001373572.1  next to BRCA1 gene 1 protein

    Status: VALIDATED

    Source sequence(s)
    CT583642
    UniProtKB/TrEMBL
    A0A8M1QKU5, F1R2I7
    Related
    ENSDARP00000104318.2, ENSDART00000112742.3
    Conserved Domains (4) summary
    cd06396
    Location:585
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd14319
    Location:944980
    UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
    cd14947
    Location:363470
    NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
    cl00295
    Location:223261
    ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    32933721..32952043
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474335.2XP_021330010.1  next to BRCA1 gene 1 protein isoform X1

    UniProtKB/TrEMBL
    A0A8M1QKU5, A0A8M9Q9K6
    Conserved Domains (3) summary
    cd06396
    Location:585
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd14319
    Location:930966
    UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
    cd14947
    Location:349456
    NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395227.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    277510..297095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)