ddx1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ddx1provided by ZNC
Official Full Name: DEAD (Asp-Glu-Ala-Asp) box helicase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-041001-215
See related: Ensembl:ENSDARG00000032117 AllianceGenome:ZFIN:ZDB-GENE-041001-215
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-214k9.2; si:dkey-161f12.1
Summary: Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and exonuclease activity. Predicted to act upstream of or within tRNA processing. Orthologous to human DDX1 (DEAD-box helicase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 20

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (33175190..33189652)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (33272311..33286773)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables exonuclease activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nuclease activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: ATP-dependent RNA helicase DDX1

Names: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1

NP_001184253.1

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001197324.1 → NP_001184253.1 ATP-dependent RNA helicase DDX1

Status: PROVISIONAL

Source sequence(s)

BX005358, BX649472

UniProtKB/TrEMBL

A0A8M1NW84, F1R2L8

Related

ENSDARP00000008636.7, ENSDART00000023963.10

Conserved Domains (5) summary

smart00487
Location:238 → 439

DEXDc; DEAD-like helicases superfamily

COG0513
Location:1 → 62

SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]

pfam00271
Location:493 → 609

Helicase_C; Helicase conserved C-terminal domain

cd12873
Location:93 → 245

SPRY_DDX1; SPRY domain associated with DEAD box gene DDX1

cl21455
Location:266 → 426

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases