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mettl13 methyltransferase 13, eEF1A lysine and N-terminal methyltransferase [ Danio rerio (zebrafish) ]

Gene ID: 557908, updated on 2-Nov-2024

Summary

Official Symbol
mettl13provided by ZNC
Official Full Name
methyltransferase 13, eEF1A lysine and N-terminal methyltransferaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-60
See related
Ensembl:ENSDARG00000010905 AllianceGenome:ZFIN:ZDB-GENE-060929-60
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
eef1aknmt; zgc:152769; si:dkey-19f21.2
Summary
Predicted to enable protein-lysine N-methyltransferase activity. Predicted to act upstream of or within methylation. Is expressed in brain; heart; inner ear; and swim bladder. Orthologous to human METTL13 (methyltransferase 13, eEF1A N-terminus and K55). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See mettl13 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (14927728..14941080, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (15031748..15045100, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene dynamin 3a Neighboring gene microRNA 199-3a Neighboring gene microRNA 214a Neighboring gene inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Neighboring gene vesicle-associated membrane protein 4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables catalytic activity  
enables methyltransferase activity  
enables protein-lysine N-methyltransferase activity  
enables transferase activity  
Component Evidence Code Pubs
is_active_in cellular_component  

General protein information

Preferred Names
eEF1A lysine and N-terminal methyltransferase
Names
methyltransferase like 13
methyltransferase-like protein 13
NP_001038234.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044769.4NP_001038234.3  eEF1A lysine and N-terminal methyltransferase

    Status: VALIDATED

    Source sequence(s)
    BX470128
    UniProtKB/Swiss-Prot
    A5WVX1, Q567H9
    UniProtKB/TrEMBL
    A0A8M1N9K6, G1K2I9
    Related
    ENSDARP00000026819.9, ENSDART00000021394.11
    Conserved Domains (2) summary
    cl09608
    Location:125238
    Cas7_I-E; CRISPR/Cas system-associated RAMP superfamily protein Cas7
    cl17173
    Location:53155
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    14927728..14941080 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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