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macc1 MET transcriptional regulator MACC1 [ Danio rerio (zebrafish) ]

Gene ID: 558777, updated on 2-Nov-2024

Summary

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Official Symbol
macc1provided by ZNC
Official Full Name
MET transcriptional regulator MACC1provided by ZNC
Primary source
ZFIN:ZDB-GENE-091006-3
See related
Ensembl:ENSDARG00000040717 AllianceGenome:ZFIN:ZDB-GENE-091006-3
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Acts upstream of or within embryonic cranial skeleton morphogenesis. Predicted to be active in cytoplasm. Is expressed in eye; midbrain hindbrain boundary; otic vesicle; stomodeum; and telencephalon. Orthologous to human MACC1 (MET transcriptional regulator MACC1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See macc1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (19637433..19644458)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (19831626..19838639)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family B (MDR/TAP), member 5 Neighboring gene uncharacterized LOC108179597 Neighboring gene transmembrane protein 196b Neighboring gene twist family bHLH transcription factor 1b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis. Melvin VS, et al. Dev Dyn, 2013 Jul. PMID 23559552, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within embryonic cranial skeleton morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
metastasis-associated in colon cancer protein 1
Names
metastasis associated in colon cancer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199766.1 → NP_001186695.1  metastasis-associated in colon cancer protein 1

    Status: VALIDATED

    Source sequence(s)
    BX005389
    UniProtKB/TrEMBL
    A0A8M1NXI5, E7FG38
    Related
    ENSDARP00000114832.1, ENSDART00000135359.2
    Conserved Domains (4) summary
    cd01670
    Location:747 → 822
    Death; Death Domain: a protein-protein interaction domain
    cl02517
    Location:220 → 261
    ZU5; ZU5 domain
    cl14633
    Location:660 → 741
    DD; Death Domain Superfamily of protein-protein interaction domains
    cl17036
    Location:557 → 621
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    19637433..19644458
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213975.1 → XP_068070076.1  metastasis-associated in colon cancer protein 1 isoform X1

    Related
    ENSDARP00000151857.1, ENSDART00000184773.1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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