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unm_hu7910 un-named hu7910 [ Danio rerio (zebrafish) ]

Gene ID: 559236, updated on 18-Sep-2024

Summary

Official Symbol
unm_hu7910provided by ZNC
Official Full Name
un-named hu7910provided by ZNC
Primary source
ZFIN:ZDB-GENE-120727-22
See related
Ensembl:ENSDARG00000078703 AllianceGenome:ZFIN:ZDB-GENE-120727-22
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable peptidyl-aspartic acid 3-dioxygenase activity. Predicted to act upstream of or within peptidyl-aspartic acid hydroxylation. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Orthologous to human ASPH (aspartate beta-hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See unm_hu7910 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (58186633..58251443, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (57884193..57949025, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene ankyrin 2b, neuronal Neighboring gene neutral sphingomyelinase (N-SMase) activation associated factor Neighboring gene gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) Neighboring gene syndecan binding protein (syntenin) Neighboring gene cytochrome P450, family 7, subfamily A, polypeptide 1b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables peptidyl-aspartic acid 3-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within peptidyl-aspartic acid hydroxylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
aspartyl/asparaginyl beta-hydroxylase; calponin homology domain-containing protein DDB_G0272472
Names
unm_sa2365
XP_009301795.1
XP_021333678.1
XP_068078843.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    58186633..58251443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021478003.2XP_021333678.1  aspartyl/asparaginyl beta-hydroxylase isoform X3

    UniProtKB/TrEMBL
    A0A2R8QJF6, A0A8M9Q2V6
    Related
    ENSDARP00000152441.1, ENSDART00000185189.1
    Conserved Domains (4) summary
    pfam05279
    Location:26253
    Asp-B-Hydro_N; Aspartyl beta-hydroxylase N-terminal region
    sd00006
    Location:264290
    TPR; TPR repeat [structural motif]
    pfam05118
    Location:433586
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase
    cl26002
    Location:180363
    TPR_11; TPR repeat
  2. XM_068222742.1XP_068078843.1  calponin homology domain-containing protein DDB_G0272472 isoform X1

  3. XM_009303520.4XP_009301795.1  calponin homology domain-containing protein DDB_G0272472 isoform X2

    See identical proteins and their annotated locations for XP_009301795.1

    UniProtKB/TrEMBL
    A0A8M3B1J7
    Conserved Domains (2) summary
    pfam05279
    Location:29273
    Asp-B-Hydro_N; Aspartyl beta-hydroxylase N-terminal region
    pfam13868
    Location:298589
    TPH; Trichohyalin-plectin-homology domain