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dnajc18 DnaJ (Hsp40) homolog, subfamily C, member 18 [ Danio rerio (zebrafish) ]

Gene ID: 559928, updated on 12-Sep-2024

Summary

Official Symbol
dnajc18provided by ZNC
Official Full Name
DnaJ (Hsp40) homolog, subfamily C, member 18provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-8019
See related
Ensembl:ENSDARG00000056005 AllianceGenome:ZFIN:ZDB-GENE-030131-8019
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj47b06; wu:fj47b06; zgc:172228
Summary
Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein; chaperone cofactor-dependent protein refolding; and ubiquitin-dependent ERAD pathway. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DNAJC18 (DnaJ heat shock protein family (Hsp40) member C18). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See dnajc18 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (30239549..30254049, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (30202854..30217354, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488826 Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene bromodomain containing 8a Neighboring gene family with sequence similarity 53 member C Neighboring gene stem-loop binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables Hsp70 protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in cellular response to misfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dnaJ homolog subfamily C member 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113588.1NP_001107060.1  dnaJ homolog subfamily C member 18

    See identical proteins and their annotated locations for NP_001107060.1

    Status: PROVISIONAL

    Source sequence(s)
    BC154601
    UniProtKB/TrEMBL
    A8WG70, B7ZV24, F6NXK8
    Related
    ENSDARP00000091828.4, ENSDART00000101054.5
    Conserved Domains (2) summary
    pfam00226
    Location:121182
    DnaJ; DnaJ domain
    pfam09320
    Location:299399
    DUF1977; Domain of unknown function (DUF1977)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    30239549..30254049 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)