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hpdl 4-hydroxyphenylpyruvate dioxygenase-like [ Danio rerio (zebrafish) ]

Gene ID: 560428, updated on 2-Nov-2024

Summary

Official Symbol
hpdlprovided by ZNC
Official Full Name
4-hydroxyphenylpyruvate dioxygenase-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-071004-50
See related
Ensembl:ENSDARG00000101010 AllianceGenome:ZFIN:ZDB-GENE-071004-50
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj39d06; wu:fj39d06; zgc:171978
Summary
Predicted to enable 4-hydroxyphenylpyruvate dioxygenase activity and metal ion binding activity. Predicted to act upstream of or within aromatic amino acid metabolic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 83. Orthologous to human HPDL (4-hydroxyphenylpyruvate dioxygenase like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See hpdl in Genome Data Viewer
Location:
chromosome: 12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (46869283..46881002)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (46853083..46864817)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene vinculin b Neighboring gene adenosine kinase b Neighboring gene family with sequence similarity 53 member B Neighboring gene phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in Golgi membrane  
is_active_in cellular_component  

General protein information

Preferred Names
4-hydroxyphenylpyruvate dioxygenase-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109708.1NP_001103178.1  4-hydroxyphenylpyruvate dioxygenase-like protein

    See identical proteins and their annotated locations for NP_001103178.1

    Status: PROVISIONAL

    Source sequence(s)
    BC152021
    UniProtKB/TrEMBL
    A7MC29
    Conserved Domains (3) summary
    cd07250
    Location:175399
    HPPD_C_like; C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS)
    TIGR01263
    Location:6413
    4HPPD; 4-hydroxyphenylpyruvate dioxygenase
    cl14632
    Location:8160
    Glo_EDI_BRP_like; This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    46869283..46881002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017358464.3XP_017213953.1  4-hydroxyphenylpyruvate dioxygenase-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8M6Z8W4, E7FH29
    Related
    ENSDARP00000134471.1, ENSDART00000166560.2
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