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htra2-8 HtrA serine peptidase 2-8 [ Danio rerio (zebrafish) ]

Gene ID: 560704, updated on 12-Sep-2024

Summary

Official Symbol
htra2-8provided by ZNC
Official Full Name
HtrA serine peptidase 2-8provided by ZNC
Primary source
ZFIN:ZDB-GENE-081028-29
See related
AllianceGenome:ZFIN:ZDB-GENE-081028-29
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-33c12.11
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in positive regulation of apoptotic process; programmed cell death; and proteolysis. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See htra2-8 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (9188072..9210001, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (8856371..8862606, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene HtrA serine peptidase 2-7 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 156 Neighboring gene si:dkey-33c12.12 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 158

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in positive regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in programmed cell death IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
serine protease HTRA2, mitochondrial
Names
novel serine protease protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    9188072..9210001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213136.1XP_068069237.1  serine protease HTRA2, mitochondrial

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394865.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    352079..374010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068218710.1XP_068074811.1  serine protease HTRA2, mitochondrial