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ppp6r2a protein phosphatase 6, regulatory subunit 2a [ Danio rerio (zebrafish) ]

Gene ID: 560729, updated on 2-Nov-2024

Summary

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Official Symbol
ppp6r2aprovided by ZNC
Official Full Name
protein phosphatase 6, regulatory subunit 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5428
See related
Ensembl:ENSDARG00000045540 AllianceGenome:ZFIN:ZDB-GENE-030131-5428
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
saps2; ppp6r2; fd18a05; wu:fd18a05; zgc:136621; si:dkey-159a18.3
Summary
Predicted to enable protein phosphatase regulator activity. Predicted to be involved in regulation of signal transduction. Predicted to be active in cytosol and nucleus. Orthologous to human PPP6R2 (protein phosphatase 6 regulatory subunit 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See ppp6r2a in Genome Data Viewer
Location:
chromosome: 4
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (20082475..20101740)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (20093499..20109782)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene GRIP and coiled-coil domain containing 1 Neighboring gene DENN/MADD domain containing 6B Neighboring gene si:dkey-159a18.1 Neighboring gene coiled-coil domain containing 146 Neighboring gene FAM3 metabolism regulating signaling molecule C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC136621

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein phosphatase binding IEA
Inferred from Electronic Annotation
more info
  
enables protein phosphatase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
serine/threonine-protein phosphatase 6 regulatory subunit 2a
Names
SAPS domain family, member 2
protein phosphatase 6, regulatory subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025509.1 → NP_001020680.1  serine/threonine-protein phosphatase 6 regulatory subunit 2a

    See identical proteins and their annotated locations for NP_001020680.1

    Status: PROVISIONAL

    Source sequence(s)
    BX890616
    UniProtKB/TrEMBL
    Q1RM06, Q5RGI5
    Related
    ENSDARP00000066960.5, ENSDART00000066961.6
    Conserved Domains (2) summary
    pfam03157
    Location:697 → 820
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam04499
    Location:128 → 537
    SAPS; SIT4 phosphatase-associated protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    20082475..20101740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021475043.2 → XP_021330718.1  serine/threonine-protein phosphatase 6 regulatory subunit 2a isoform X1

    UniProtKB/TrEMBL
    Q1RM06, Q5RGI5
    Related
    ENSDARP00000152642.1, ENSDART00000188635.1
    Conserved Domains (2) summary
    pfam03157
    Location:697 → 820
    Glutenin_hmw; High molecular weight glutenin subunit
    pfam04499
    Location:128 → 537
    SAPS; SIT4 phosphatase-associated protein
Nucleotide Protein Strain
Heading Accession and Version

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