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lonrf4 LON peptidase N-terminal domain and ring finger 4 [ Danio rerio (zebrafish) ]

Gene ID: 560773, updated on 17-Sep-2024

Summary

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Official Symbol
lonrf4provided by ZNC
Official Full Name
LON peptidase N-terminal domain and ring finger 4provided by ZNC
Primary source
ZFIN:ZDB-GENE-101021-4
See related
Ensembl:ENSDARG00000075048 AllianceGenome:ZFIN:ZDB-GENE-101021-4
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
lonrf1; si:ch1073-193f3.1
Summary
Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See lonrf4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (34068069..34091017)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (33727748..33752431)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene IL2 inducible T cell kinase Neighboring gene mediator complex subunit 7 Neighboring gene glutamate receptor, ionotropic, AMPA 1a Neighboring gene uncharacterized LOC137487601

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Thyrotroph embryonic factor regulates light-induced transcription of repair genes in zebrafish embryonic cells. Gavriouchkina D, et al. PLoS One, 2010 Sep 7. PMID 20830285, Free PMC Article
  2. The light responsive transcriptome of the zebrafish: function and regulation. Weger BD, et al. PLoS One, 2011 Feb 15. PMID 21390203, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
LON peptidase N-terminal domain and RING finger protein 1
Names
LON peptidase N-terminal domain and ring finger 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    34068069..34091017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481225.2 → XP_021336900.1  LON peptidase N-terminal domain and RING finger protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QPJ1, E9QIP2
    Related
    ENSDARP00000113687.1, ENSDART00000135556.4
    Conserved Domains (4) summary
    sd00006
    Location:108 → 138
    TPR; TPR repeat [structural motif]
    cd16514
    Location:303 → 344
    RING2-HC_LONFs; RING finger 2, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
    cl17238
    Location:9 → 47
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl19481
    Location:385 → 591
    LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain

RNA

  1. XR_011006238.1 RNA Sequence

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394918.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    231242..255537
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_684170.10 → XP_689262.3  LON peptidase N-terminal domain and RING finger protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9QPJ1, E9QIP2
    Conserved Domains (4) summary
    sd00006
    Location:108 → 138
    TPR; TPR repeat [structural motif]
    cd16514
    Location:303 → 344
    RING2-HC_LONFs; RING finger 2, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
    cl17238
    Location:9 → 47
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl19481
    Location:385 → 591
    LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain

RNA

  1. XR_002457391.2 RNA Sequence

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395316.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    251473..264692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474313.2 → XP_021329988.2  LON peptidase N-terminal domain and RING finger protein 1 isoform X2

Nucleotide Protein Strain
Heading Accession and Version

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