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snx18a sorting nexin 18a [ Danio rerio (zebrafish) ]

Gene ID: 562372, updated on 12-Sep-2024

Summary

Official Symbol
snx18aprovided by ZNC
Official Full Name
sorting nexin 18aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070705-339
See related
Ensembl:ENSDARG00000067713 AllianceGenome:ZFIN:ZDB-GENE-070705-339
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-193c22.4
Summary
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to act upstream of or within mitotic cell cycle and protein transport. Predicted to be located in cytoplasmic vesicle membrane. Orthologous to human SNX18 (sorting nexin 18). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See snx18a in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (40272848..40292299, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (39672695..39692146, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene si:dkey-193c22.1 Neighboring gene chondroitin sulfate proteoglycan 4ba Neighboring gene ADP-ribosylation factor-like 15a Neighboring gene heat shock protein, alpha-crystallin-related, b3 Neighboring gene NADH:ubiquinone oxidoreductase subunit S4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cleavage furrow formation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
 
involved_in endosomal transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in plasma membrane tubulation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
sorting nexin-18a
Names
snag1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100006.1NP_001093476.1  sorting nexin-18a

    See identical proteins and their annotated locations for NP_001093476.1

    Status: PROVISIONAL

    Source sequence(s)
    BX571674
    UniProtKB/TrEMBL
    A0A2R8Q0F4, A5PMM5
    Related
    ENSDARP00000088296.4, ENSDART00000097525.5
    Conserved Domains (3) summary
    cd07286
    Location:221347
    PX_SNX18; The phosphoinositide binding Phox Homology domain of Sorting Nexin 18
    cd07670
    Location:358564
    BAR_SNX18; The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexin 18
    cl17036
    Location:458
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    40272848..40292299 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394601.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    95534..115173 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)