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ppp1r13ba protein phosphatase 1, regulatory subunit 13Ba [ Danio rerio (zebrafish) ]

Gene ID: 563577, updated on 28-Oct-2024

Summary

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Official Symbol
ppp1r13baprovided by ZNC
Official Full Name
protein phosphatase 1, regulatory subunit 13Baprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9805
See related
Ensembl:ENSDARG00000004377 AllianceGenome:ZFIN:ZDB-GENE-030131-9805
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb375; fc63g02; fc76b12; sb:cb375; wu:fa02c01; wu:fb69g10; wu:fc63g02; wu:fc76b12; si:ch73-9j13.1
Summary
Predicted to enable p53 binding activity. Predicted to act upstream of or within regulation of apoptotic process. Predicted to be active in nucleus. Is expressed in several structures, including cardiovascular system; hematopoietic system; musculature system; nervous system; and neural tube. Orthologous to human PPP1R13B (protein phosphatase 1 regulatory subunit 13B). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See ppp1r13ba in Genome Data Viewer
Location:
chromosome: 17
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (14614137..14691622, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (14606207..14683703, complement)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene dishevelled associated activator of morphogenesis 1a Neighboring gene serine dehydratase-like Neighboring gene protein tyrosine phosphatase 4A2a Neighboring gene gap junction protein beta 9a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Retinoic acid receptor subtype-specific transcriptotypes in the early zebrafish embryo. Samarut E, et al. Mol Endocrinol, 2014 Feb. PMID 24422634, Free PMC Article
  2. Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish. Gomez G, et al. PLoS One, 2012. PMID 22438865, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables p53 binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables p53 binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein phosphatase 1, regulatory subunit 13Ba

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001204257.1 → NP_001191186.1  protein phosphatase 1, regulatory subunit 13Ba

    Status: VALIDATED

    Source sequence(s)
    CU469548, FP067407
    UniProtKB/TrEMBL
    A0A8M1P3N6, F1RDT1
    Related
    ENSDARP00000028707.7, ENSDART00000037371.8
    Conserved Domains (5) summary
    cd00204
    Location:906 → 1029
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:912 → 1003
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:912 → 938
    ANK; ANK repeat [structural motif]
    cl09111
    Location:240 → 368
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl17036
    Location:1042 → 1098
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    14614137..14691622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009292888.4 → XP_009291163.1  protein phosphatase 1, regulatory subunit 13Ba isoform X2

    UniProtKB/TrEMBL
    A0A8M3AU31
    Conserved Domains (5) summary
    cd00204
    Location:878 → 1001
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:884 → 975
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:884 → 910
    ANK; ANK repeat [structural motif]
    cl09111
    Location:212 → 340
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl17036
    Location:1014 → 1070
    SH3; Src Homology 3 domain superfamily

  2. XM_009292889.4 → XP_009291164.1  protein phosphatase 1, regulatory subunit 13Ba isoform X3

    UniProtKB/TrEMBL
    A0A8M3AR73
    Conserved Domains (5) summary
    cd00204
    Location:873 → 996
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:879 → 970
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:879 → 905
    ANK; ANK repeat [structural motif]
    cl09111
    Location:247 → 375
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl17036
    Location:1009 → 1065
    SH3; Src Homology 3 domain superfamily

  3. XM_009292887.4 → XP_009291162.1  protein phosphatase 1, regulatory subunit 13Ba isoform X1

    UniProtKB/TrEMBL
    A0A8M3AJN6
    Conserved Domains (5) summary
    cd00204
    Location:913 → 1036
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:919 → 1010
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:919 → 945
    ANK; ANK repeat [structural motif]
    cl09111
    Location:247 → 375
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl17036
    Location:1049 → 1105
    SH3; Src Homology 3 domain superfamily

  4. XM_009292890.3 → XP_009291165.1  protein phosphatase 1, regulatory subunit 13Ba isoform X4

    UniProtKB/TrEMBL
    A0A8M3AIS3
    Conserved Domains (5) summary
    cd00204
    Location:802 → 925
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:808 → 899
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:808 → 834
    ANK; ANK repeat [structural motif]
    cl09111
    Location:136 → 264
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl17036
    Location:938 → 994
    SH3; Src Homology 3 domain superfamily

  5. XM_068214420.1 → XP_068070521.1  protein phosphatase 1, regulatory subunit 13Ba isoform X6

  6. XM_009292891.4 → XP_009291166.1  protein phosphatase 1, regulatory subunit 13Ba isoform X5

    UniProtKB/TrEMBL
    A0A8M3B283
    Conserved Domains (5) summary
    cd00204
    Location:797 → 920
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:803 → 894
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:803 → 829
    ANK; ANK repeat [structural motif]
    cl09111
    Location:131 → 259
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    cl17036
    Location:933 → 989
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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