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pof1b POF1B actin binding protein [ Danio rerio (zebrafish) ]

Gene ID: 564098, updated on 2-Nov-2024

Summary

Official Symbol
pof1bprovided by ZNC
Official Full Name
POF1B actin binding proteinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4287
See related
Ensembl:ENSDARG00000054060 AllianceGenome:ZFIN:ZDB-GENE-030131-4287
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc88b11; wu:fa99b01; wu:fc88b11; si:dkeyp-8h9.2
Summary
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization; bicellular tight junction assembly; and epithelial cell morphogenesis. Predicted to be active in actin filament; adherens junction; and bicellular tight junction. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 2B. Orthologous to human POF1B (POF1B actin binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See pof1b in Genome Data Viewer
Location:
chromosome: 21
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (38513532..38581880, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (38465551..38534322, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene POU class 4 homeobox 4 Neighboring gene protein sprouty homolog 2 Neighboring gene solute carrier family 25 member 14 Neighboring gene G protein-coupled receptor 119

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in epithelial cell morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in actin filament IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein POF1B
Names
premature ovarian failure, 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    38513532..38581880 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068216131.1XP_068072232.1  protein POF1B isoform X1

    Related
    ENSDARP00000124164.2, ENSDART00000148939.3

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395097.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    326154..389957 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068218980.1XP_068075081.1  protein POF1B isoform X1

  2. XM_002666059.7XP_002666105.6  protein POF1B isoform X2

  3. XM_068218979.1XP_068075080.1  protein POF1B isoform X2