st13 ST13 Hsp70 interacting protein [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: st13provided by ZNC
Official Full Name: ST13 Hsp70 interacting proteinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5395
See related: Ensembl:ENSDARG00000021973 AllianceGenome:ZFIN:ZDB-GENE-030131-5395
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73267; wu:fd15g02
Summary: Predicted to enable heat shock protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein-containing complex assembly. Orthologous to several human genes including ST13 (ST13 Hsp70 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (25087627..25100726)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (24957079..24970178)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc42b05.y1 (e-PCR)
- UniSTS:193803

fd15g02.x1 (e-PCR)
- UniSTS:204203

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables Hsp70 protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chaperone cofactor-dependent protein refolding	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: hsc70-interacting protein

Names: suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199769.2 → NP_956063.1 hsc70-interacting protein

See identical proteins and their annotated locations for NP_956063.1

Status: PROVISIONAL

Source sequence(s)

BX470254, DR728308, DR729501, EB881211

UniProtKB/TrEMBL

Q6NX98, Q6P4P4

Related

ENSDARP00000112549.1, ENSDART00000138578.2

Conserved Domains (5) summary

smart00727
Location:311 → 350

STI1; Heat shock chaperonin-binding motif

cd14438
Location:3 → 43

Hip_N; N-terminal dimerization domain of the Hsp70-interacting protein (Hip) and similar proteins

sd00006
Location:117 → 145

TPR; TPR repeat [structural motif]

pfam00515
Location:151 → 183

TPR_1; Tetratricopeptide repeat

pfam13414
Location:116 → 182

TPR_11; TPR repeat