rps6kc1 ribosomal protein S6 kinase polypeptide 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rps6kc1provided by ZNC
Official Full Name: ribosomal protein S6 kinase polypeptide 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-081031-83
See related: Ensembl:ENSDARG00000104103 AllianceGenome:ZFIN:ZDB-GENE-081031-83
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: im:7140066; si:zfos-692b10.1; si:ch1073-412h12.1
Summary: Predicted to enable ATP binding activity; phosphatidylinositol binding activity; and protein kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in early endosome. Is expressed in central nervous system and retina. Orthologous to human RPS6KC1 (ribosomal protein S6 kinase C1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	20	NC_007131.7 (3238983..3276385, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	20	NC_007131.6 (3221482..3258845, complement)

Chromosome 20 - NC_007131.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in early endosome	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ribosomal protein S6 kinase delta-1

Names: novel PX domain containing protein; ribosomal protein S6 kinase c, polypeptide 1

NP_001352480.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001365551.1 → NP_001352480.1 ribosomal protein S6 kinase delta-1

Status: VALIDATED

Source sequence(s)

CU550712, CU693438

UniProtKB/TrEMBL

A0A0R4IV01, A0A8M3AT05

Related

ENSDARP00000141281.1, ENSDART00000166831.2

Conserved Domains (3) summary

cd07287
Location:10 → 127

PX_RPK118_like; The phosphoinositide binding Phox Homology domain of RPK118-like proteins

cd02677
Location:231 → 299

MIT_SNX15; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This MIT domain sub-family is found in sorting nexin 15 and related proteins. The molecular function of the MIT domain is unclear.

cl21453
Location:743 → 918

PKc_like; Protein Kinases, catalytic domain