med13b mediator complex subunit 13b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: med13bprovided by ZNC
Official Full Name: mediator complex subunit 13bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-3529
See related: Ensembl:ENSDARG00000003910 AllianceGenome:ZFIN:ZDB-GENE-030131-3529
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: med13; fc43h07; fc43h08; wu:fb66c06; wu:fc43h07; wu:fc43h08; zgc:153454
Summary: Predicted to enable transcription coactivator activity. Acts upstream of or within neural crest cell migration. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is expressed in blastomere; nervous system; pectoral fin; and pectoral fin bud. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder. Orthologous to human MED13 (mediator complex subunit 13). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 15

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (20060643..20125164, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (20124911..20189432, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fc43h07.x1 (e-PCR)
- UniSTS:203921

AI545943 (e-PCR)
- UniSTS:206276

fb66c06.y1 (e-PCR)
- UniSTS:190921

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables transcription coactivator activity	IBA Inferred from Biological aspect of Ancestor more info
enables transcription coregulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within neural crest cell migration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of mediator complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mediator complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mediator of RNA polymerase II transcription subunit 13-like

Names: mediator complex subunit 13; thyroid hormone receptor-associated protein complex 240 kDa component-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.