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stk40 serine/threonine kinase 40 [ Danio rerio (zebrafish) ]

Gene ID: 564859, updated on 14-Nov-2024

Summary

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Official Symbol
stk40provided by ZNC
Official Full Name
serine/threonine kinase 40provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-4831
See related
Ensembl:ENSDARG00000098135 AllianceGenome:ZFIN:ZDB-GENE-030131-4831
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb988; fd99h11; wu:fd99h11
Summary
Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in regulation of MAPK cascade. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytoplasm. Is expressed in axis; hindbrain neural plate; mesoderm; optic primordium; and optic vesicle. Orthologous to human STK40 (serine/threonine kinase 40). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See stk40 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (36035086..36073072, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (36465355..36490700)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene SH3 domain containing 21 Neighboring gene eva-1 homolog Ba (C. elegans) Neighboring gene organic solute carrier partner 1b Neighboring gene mitochondrial ribosomal protein S15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine/threonine-protein kinase 40
XP_021322631.1
XP_021322632.1
XP_068070273.1
XP_693275.6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    36035086..36073072 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466957.2 → XP_021322632.1  serine/threonine-protein kinase 40 isoform X1

    UniProtKB/TrEMBL
    A0A8M9NZS1
    Conserved Domains (1) summary
    cd13974
    Location:68 → 359
    STKc_SHIK; Catalytic domain of the Serine/Threonine kinase, SINK-homologous inhibitory kinase

  2. XM_021466956.2 → XP_021322631.1  serine/threonine-protein kinase 40 isoform X2

    UniProtKB/TrEMBL
    A0A8M9NZS1
    Conserved Domains (1) summary
    cd13974
    Location:68 → 359
    STKc_SHIK; Catalytic domain of the Serine/Threonine kinase, SINK-homologous inhibitory kinase

  3. XM_068214172.1 → XP_068070273.1  serine/threonine-protein kinase 40 isoform X3

    Related
    ENSDARP00000152314.1, ENSDART00000182584.1

  4. XM_688183.10 → XP_693275.6  serine/threonine-protein kinase 40 isoform X4

    UniProtKB/TrEMBL
    A0A0R4IDK5, A0A8N7UV17
    Related
    ENSDARP00000130758.2, ENSDART00000158358.2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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