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map7d1a MAP7 domain containing 1a [ Danio rerio (zebrafish) ]

Gene ID: 565172, updated on 14-Nov-2024

Summary

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Official Symbol
map7d1aprovided by ZNC
Official Full Name
MAP7 domain containing 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-22
See related
Ensembl:ENSDARG00000098802 AllianceGenome:ZFIN:ZDB-GENE-060503-22
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-207m11.1
Summary
Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in microtubule cytoskeleton. Is expressed in ciliary marginal zone. Orthologous to human MAP7D1 (MAP7 domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See map7d1a in Genome Data Viewer
Location:
chromosome: 16
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (35661726..35773210)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (35708851..35820335)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene si:ch211-1i11.3 Neighboring gene uncharacterized LOC137487937 Neighboring gene uncharacterized LOC137487848 Neighboring gene uncharacterized LOC137487938

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure. Li LP, et al. Biomed Res Int, 2021. PMID 34327238, Free PMC Article
  2. Forward Genetic Screening Using Behavioral Tests in Zebrafish: A Proof of Concept Analysis of Mutants. Gerlai R, et al. Behav Genet, 2017 Jan. PMID 27704300
  3. Reverse genetic analysis of neurogenesis in the zebrafish retina. Pujic Z, et al. Dev Biol, 2006 May 15. PMID 16603149
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure.
    Title: Disruption of MAP7D1 Gene Function Increases the Risk of Doxorubicin-Induced Cardiomyopathy and Heart Failure.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in microtubule cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
MAP7 domain-containing protein 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001326399.1 → NP_001313328.1  MAP7 domain-containing protein 1a

    Status: VALIDATED

    Source sequence(s)
    AL773558, FQ377622
    UniProtKB/TrEMBL
    A0A0R4IEP5, A0A8M1P8Y2
    Related
    ENSDARP00000132764.1, ENSDART00000161393.2
    Conserved Domains (3) summary
    pfam05672
    Location:499 → 659
    MAP7; MAP7 (E-MAP-115) family
    cd16269
    Location:166 → 178
    GBP_C; coiled coil [structural motif]
    cl20817
    Location:95 → 192
    GBP_C; Guanylate-binding protein, C-terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    35661726..35773210
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021466720.2 → XP_021322395.1  MAP7 domain-containing protein 1a isoform X2

    UniProtKB/TrEMBL
    A0A8M9PMI8
    Conserved Domains (3) summary
    pfam05672
    Location:513 → 673
    MAP7; MAP7 (E-MAP-115) family
    cl25602
    Location:92 → 179
    DUF3552; Domain of unknown function (DUF3552)
    cl26464
    Location:287 → 519
    Atrophin-1; Atrophin-1 family

  2. XM_068213984.1 → XP_068070085.1  MAP7 domain-containing protein 1a isoform X1

  3. XM_068213986.1 → XP_068070087.1  MAP7 domain-containing protein 1a isoform X4

  4. XM_068213987.1 → XP_068070088.1  MAP7 domain-containing protein 1a isoform X5

  5. XM_068213990.1 → XP_068070091.1  MAP7 domain-containing protein 1a isoform X8

  6. XM_068213989.1 → XP_068070090.1  MAP7 domain-containing protein 1a isoform X7

  7. XM_068213985.1 → XP_068070086.1  MAP7 domain-containing protein 1a isoform X3

  8. XM_068213988.1 → XP_068070089.1  MAP7 domain-containing protein 1a isoform X6

  9. XM_068213991.1 → XP_068070092.1  MAP7 domain-containing protein 1a isoform X9

Nucleotide Protein Strain
Heading Accession and Version

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