ptpdc1a protein tyrosine phosphatase domain containing 1a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ptpdc1aprovided by ZNC
Official Full Name: protein tyrosine phosphatase domain containing 1aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-070112-632
See related: Ensembl:ENSDARG00000061656 AllianceGenome:ZFIN:ZDB-GENE-070112-632
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ptpdc1; zgc:158271
Summary: Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in cilium assembly. Predicted to act upstream of or within cell projection organization and protein dephosphorylation. Predicted to be active in cytoplasm. Orthologous to human PTPDC1 (protein tyrosine phosphatase domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (27511277..27537661, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (27264035..27290487, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IEA Inferred from Electronic Annotation more info
enables phosphoprotein phosphatase activity	IEA Inferred from Electronic Annotation more info
enables protein tyrosine phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell projection organization	IEA Inferred from Electronic Annotation more info
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cilium assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within dephosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein dephosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein tyrosine phosphatase domain-containing protein 1

Names: protein tyrosine phosphatase domain containing 1

NP_001074065.2

EC 3.1.3.48

XP_021335316.1

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080596.2 → NP_001074065.2 protein tyrosine phosphatase domain-containing protein 1

Status: VALIDATED

Source sequence(s)

CR548622

UniProtKB/Swiss-Prot

A1L1R5

UniProtKB/TrEMBL

A0A8M1NCR7, F1QYQ8

Related

ENSDARP00000082610.4, ENSDART00000088177.7

Conserved Domains (1) summary

smart00404
Location:152 → 233

PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007122.7 Reference GRCz11 Primary Assembly

Range

27511277..27537661 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021479641.2 → XP_021335316.1 protein tyrosine phosphatase domain-containing protein 1 isoform X1

UniProtKB/Swiss-Prot

A1L1R5

UniProtKB/TrEMBL

A0A8M9QHQ6

Conserved Domains (1) summary

cl25998
Location:153 → 242

CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]