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tns2b tensin 2b [ Danio rerio (zebrafish) ]

Gene ID: 565809, updated on 12-Sep-2024

Summary

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Official Symbol
tns2bprovided by ZNC
Official Full Name
tensin 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-101001-5
See related
Ensembl:ENSDARG00000068397 AllianceGenome:ZFIN:ZDB-GENE-101001-5
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tenc1b; fc15a01; wu:fc15a01; si:ch211-71p22.1
Summary
Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in cell junction. Orthologous to human TNS2 (tensin 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See tns2b in Genome Data Viewer
Location:
chromosome: 6
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (39013905..39050997, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (39016367..39053827, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene vitamin D receptor b Neighboring gene transfer RNA glutamine (anticodon UUG) Neighboring gene uncharacterized LOC137495994 Neighboring gene eukaryotic translation initiation factor 4Bb

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tensin 2b; tensin-2
Names
tensin like C1 domain containing phosphatase b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    39013905..39050997 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005166088.5 → XP_005166145.1  tensin-2 isoform X2

    UniProtKB/TrEMBL
    A0A8M2BDF7
    Conserved Domains (5) summary
    cd09927
    Location:1168 → 1283
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    smart00404
    Location:191 → 304
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    cd01213
    Location:1307 → 1428
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam00130
    Location:45 → 91
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam10409
    Location:293 → 420
    PTEN_C2; C2 domain of PTEN tumour-suppressor protein

  2. XM_689077.10 → XP_694169.6  tensin-2 isoform X1

    UniProtKB/TrEMBL
    A0A8N7UT94
    Related
    ENSDARP00000089676.4, ENSDART00000098906.5
    Conserved Domains (5) summary
    cd09927
    Location:1168 → 1283
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    smart00404
    Location:191 → 304
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    cd01213
    Location:1307 → 1438
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam00130
    Location:45 → 91
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam10409
    Location:293 → 420
    PTEN_C2; C2 domain of PTEN tumour-suppressor protein

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394660.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    117735..155372 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021471814.2 → XP_021327489.1  tensin-2 isoform X2

    UniProtKB/TrEMBL
    A0A8M9PRI6
    Conserved Domains (5) summary
    cd09927
    Location:1168 → 1283
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    smart00404
    Location:191 → 304
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    cd01213
    Location:1307 → 1428
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam00130
    Location:45 → 91
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam10409
    Location:293 → 420
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein

  2. XM_021471813.2 → XP_021327488.1  tensin-2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PKG9
    Conserved Domains (5) summary
    cd09927
    Location:1168 → 1283
    SH2_Tensin_like; Src homology 2 domain found in Tensin-like proteins
    smart00404
    Location:191 → 304
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    cd01213
    Location:1307 → 1438
    PTB_tensin; Tensin Phosphotyrosine-binding (PTB) domain
    pfam00130
    Location:45 → 91
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam10409
    Location:293 → 420
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
Nucleotide Protein Strain
Heading Accession and Version

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