prkd4 protein kinase D4 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: prkd4provided by ZNC
Official Full Name: protein kinase D4provided by ZNC
Primary source: ZFIN:ZDB-GENE-080204-93
See related: Ensembl:ENSDARG00000104153 AllianceGenome:ZFIN:ZDB-GENE-080204-93
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:175248
Summary: Predicted to enable ATP binding activity and calcium-dependent protein kinase C activity. Predicted to be involved in protein kinase D signaling. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: Annotation category: partial on reference assembly
Orthologs: all
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Genomic context

Location:: chromosome: 7

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (6879534..6908645)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (6730018..6750231)
105	previous assembly	GRCz10 (GCF_000002035.5)	Unplaced Scaffold	NW_003334548.2 (3970..60615, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables diacylglycerol-dependent serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein kinase D4

NP_001170925.1

EC 2.7.11.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001177454.1 → NP_001170925.1 protein kinase D4

See identical proteins and their annotated locations for NP_001170925.1

Status: PROVISIONAL

Source sequence(s)

BC155343

UniProtKB/TrEMBL

A0A0R4IME7, A0A8M1NVQ3, A9JTH6

Related

ENSDARP00000137447.2, ENSDART00000157731.2

Conserved Domains (5) summary

smart00220
Location:352 → 604

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd00029
Location:100 → 149

C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

cd01239
Location:219 → 319

PH_PKD; Protein kinase D (PKD/PKCmu) pleckstrin homology (PH) domain

cd14082
Location:344 → 603

STKc_PKD; Catalytic domain of the Serine/Threonine kinase, Protein Kinase D

cl00040
Location:1 → 31

C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...