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exoc3l2b exocyst complex component 3-like 2b [ Danio rerio (zebrafish) ]

Gene ID: 565839, updated on 2-Nov-2024

Summary

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Official Symbol
exoc3l2bprovided by ZNC
Official Full Name
exocyst complex component 3-like 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-100728-5
See related
Ensembl:ENSDARG00000030782 AllianceGenome:ZFIN:ZDB-GENE-100728-5
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to be part of exocyst. Is expressed in hindbrain; neural crest; and pharyngeal arch. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See exoc3l2b in Genome Data Viewer
Location:
chromosome: 15
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (20139284..20200016, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (20203541..20264286, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene activator of transcription and developmental regulator AUTS2 b Neighboring gene mediator complex subunit 13b Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14Ab Neighboring gene serine peptidase inhibitor, Kunitz type, 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration. Piloto S, et al. Development, 2010 Jun. PMID 20463035, Free PMC Article
  2. A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis. Bielczyk-Maczyńska E, et al. PLoS Genet, 2014 Jul. PMID 25010335, Free PMC Article
  3. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Lang I, et al. Int J Mol Sci, 2020 Aug 9. PMID 32784920, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in exocyst localization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within exocytosis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of exocyst IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tumor necrosis factor alpha-induced protein 2
Names
exoc3l2
sec6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    20139284..20200016 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009291705.4 → XP_009289980.1  tumor necrosis factor alpha-induced protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M3B147
    Conserved Domains (1) summary
    cl19885
    Location:338 → 875
    Sec6; Exocyst complex component Sec6

  2. XM_689101.8 → XP_694193.4  tumor necrosis factor alpha-induced protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8N7TBH4, E7EY52, X1WGU0
    Related
    ENSDARP00000129449.1, ENSDART00000157149.2
    Conserved Domains (1) summary
    cl19885
    Location:282 → 819
    Sec6; Exocyst complex component Sec6

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394946.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    9555..73124 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472940.2 → XP_021328615.1  tumor necrosis factor alpha-induced protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q5H9
    Conserved Domains (1) summary
    cl19885
    Location:338 → 875
    Sec6; Exocyst complex component Sec6

  2. XM_021472941.2 → XP_021328616.1  tumor necrosis factor alpha-induced protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8N7TBH4, E7EY52, X1WGU0
    Conserved Domains (1) summary
    cl19885
    Location:282 → 819
    Sec6; Exocyst complex component Sec6
Nucleotide Protein Strain
Heading Accession and Version

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