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zgc:172136 zgc:172136 [ Danio rerio (zebrafish) ]

Gene ID: 566376, updated on 18-Sep-2024

Summary

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Official Symbol
zgc:172136provided by ZNC
Official Full Name
zgc:172136provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1008
See related
Ensembl:ENSDARG00000078741 AllianceGenome:ZFIN:ZDB-GENE-030131-1008
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fb55g02; wu:fb55g02
Summary
Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasmic side of apical plasma membrane. Is expressed in several structures, including anterior axial hypoblast; lens placode; nervous system; optic primordium; and optic vesicle. Orthologous to human FRMD1 (FERM domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See zgc:172136 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (39236141..39271225)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (39110197..39145615)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene collagen, type IX, alpha 1b Neighboring gene family with sequence similarity 135 member A Neighboring gene TAR (HIV-1) RNA binding protein 1 Neighboring gene probable methyltransferase TARBP1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in developmental process IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of hippo signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasmic side of apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC566376
Names
FERM domain-containing protein 6-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001111187.1 → NP_001104657.1  uncharacterized protein LOC566376

    See identical proteins and their annotated locations for NP_001104657.1

    Status: PREDICTED

    Source sequence(s)
    BC155611
    UniProtKB/TrEMBL
    A0A8M1NGP5, A9JRC9
    Related
    ENSDARP00000098019.2, ENSDART00000111458.3
    Conserved Domains (4) summary
    smart00295
    Location:13 → 222
    B41; Band 4.1 homologues
    cd13185
    Location:215 → 323
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    pfam00373
    Location:108 → 222
    FERM_M; FERM central domain
    pfam09379
    Location:13 → 75
    FERM_N; FERM N-terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    39236141..39271225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307480.3 → XP_009305755.1  uncharacterized protein LOC566376 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AZA5
    Conserved Domains (4) summary
    smart00295
    Location:13 → 223
    B41; Band 4.1 homologues
    cd13185
    Location:216 → 324
    FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
    pfam00373
    Location:109 → 223
    FERM_M; FERM central domain
    pfam09379
    Location:13 → 75
    FERM_N; FERM N-terminal domain
Nucleotide Protein
Heading Accession and Version

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