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ankef1a ankyrin repeat and EF-hand domain containing 1a [ Danio rerio (zebrafish) ]

Gene ID: 566413, updated on 28-Oct-2024

Summary

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Official Symbol
ankef1aprovided by ZNC
Official Full Name
ankyrin repeat and EF-hand domain containing 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041001-196
See related
Ensembl:ENSDARG00000019135 AllianceGenome:ZFIN:ZDB-GENE-041001-196
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ankrd5a; si:dkey-20n10.1
Summary
Is expressed in several structures, including digestive system; extension; forerunner cell group; otic vesicle; and pleuroperitoneal region. Orthologous to human ANKEF1 (ankyrin repeat and EF-hand domain containing 1). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See ankef1a in Genome Data Viewer
Location:
chromosome: 20
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (34868908..34902191)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (34966040..34999332)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene stathmin-like 4 Neighboring gene interleukin 17a/f3 Neighboring gene elastin microfibril interfacer 1a Neighboring gene synaptosome associated protein 25a Neighboring gene saccharopine dehydrogenase b Neighboring gene uncharacterized LOC110438184

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Regionalized Protein Localization Domains in the Zebrafish Hair Cell Kinocilium. Erickson T, et al. J Dev Biol, 2023 Jun 16. PMID 37367482, Free PMC Article
  2. Spatiotemporal expression profile of embryonic and adult ankyrin repeat and EF-hand domain containing protein 1-encoding genes ankef1a and ankef1b in zebrafish. Daniel JG, et al. Gene Expr Patterns, 2019 Dec. PMID 31520739
  3. Developmental toxicity of the novel PFOS alternative OBS in developing zebrafish: An emphasis on cilia disruption. Huang J, et al. J Hazard Mater, 2021 May 5. PMID 33223314
  4. Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish. Yuan JM, et al. J Virol, 2015 Jan. PMID 25355883, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
ankyrin repeat and EF-hand domain containing 1a; ankyrin repeat and EF-hand domain-containing protein 1a
Names
ankyrin repeat domain 5a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025543.1 → NP_001020714.1  ankyrin repeat and EF-hand domain containing 1a

    See identical proteins and their annotated locations for NP_001020714.1

    Status: PROVISIONAL

    Source sequence(s)
    BX465184
    UniProtKB/TrEMBL
    A0A5J6CZJ6, Q5TZ64
    Related
    ENSDARP00000147052.1, ENSDART00000191797.1
    Conserved Domains (3) summary
    PHA02874
    Location:508 → 739
    PHA02874; ankyrin repeat protein; Provisional
    sd00045
    Location:529 → 557
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:531 → 623
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    34868908..34902191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005160755.5 → XP_005160812.1  ankyrin repeat and EF-hand domain-containing protein 1a isoform X1

    See identical proteins and their annotated locations for XP_005160812.1

    UniProtKB/TrEMBL
    A0A5J6CZJ6, Q5TZ64
    Related
    ENSDARP00000127243.1, ENSDART00000153006.2
    Conserved Domains (3) summary
    PHA02874
    Location:508 → 739
    PHA02874; ankyrin repeat protein; Provisional
    sd00045
    Location:529 → 557
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:531 → 623
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
Heading Accession and Version

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