tsfm Ts translation elongation factor, mitochondrial [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tsfmprovided by ZNC
Official Full Name: Ts translation elongation factor, mitochondrialprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061215-17
See related: Ensembl:ENSDARG00000060748 AllianceGenome:ZFIN:ZDB-GENE-061215-17
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: EF-Ts; EF-TsMt; zgc:158429
Summary: Predicted to enable translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to act upstream of or within translation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 3. Orthologous to human TSFM (Ts translation elongation factor, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (39897543..39903338, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (39900007..39905802, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables translation elongation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitochondrial translational elongation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: elongation factor Ts, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080035.1 → NP_001073504.1 elongation factor Ts, mitochondrial

See identical proteins and their annotated locations for NP_001073504.1

Status: PROVISIONAL

Source sequence(s)

BC128869

UniProtKB/Swiss-Prot

A1A5Z3

Related

ENSDARP00000080380.4, ENSDART00000085945.5

Conserved Domains (3) summary

PRK09377
Location:38 → 300

tsf; elongation factor Ts; Provisional

cd14275
Location:38 → 74

UBA_EF-Ts; UBA domain found in elongation factor Ts (EF-Ts) from bacteria, chloroplasts and mitochondria of eukaryotes

pfam00889
Location:106 → 300

EF_TS; Elongation factor TS