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sfr1 SWI5-dependent homologous recombination repair protein 1 [ Danio rerio (zebrafish) ]

Gene ID: 568747, updated on 2-Nov-2024

Summary

Official Symbol
sfr1provided by ZNC
Official Full Name
SWI5-dependent homologous recombination repair protein 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-070410-27
See related
Ensembl:ENSDARG00000021974 AllianceGenome:ZFIN:ZDB-GENE-070410-27
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
meir5; zgc:162162
Summary
Predicted to enable nuclear receptor coactivator activity. Predicted to be involved in double-strand break repair via homologous recombination and positive regulation of DNA-templated transcription. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Predicted to be part of Swi5-Sfr1 complex. Orthologous to human SFR1 (SWI5 dependent homologous recombination repair protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See sfr1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (24742724..24745263, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (24612274..24614708, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene sperm flagellar 1 Neighboring gene ER lipid raft associated 1 Neighboring gene cilia and flagella associated protein 43 Neighboring gene collagen, type XVII, alpha 1b Neighboring gene STE20-like kinase a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Clone Names

  • MGC162162

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables nuclear receptor coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nuclear receptor coactivator activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in double-strand break repair via homologous recombination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of Swi5-Sfr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Swi5-Sfr1 complex IEA
Inferred from Electronic Annotation
more info
 
part_of Swi5-Sfr1 complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
swi5-dependent recombination DNA repair protein 1 homolog
Names
MEI5 meiotic recombination protein homolog
SWI5-dependent recombination repair 1
meiosis protein 5 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082860.1NP_001076329.1  swi5-dependent recombination DNA repair protein 1 homolog

    See identical proteins and their annotated locations for NP_001076329.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133892
    UniProtKB/Swiss-Prot
    A3KNK5, B7ZD04
    Related
    ENSDARP00000037070.6, ENSDART00000031564.8
    Conserved Domains (1) summary
    pfam10376
    Location:21192
    Mei5; Double-strand recombination repair protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    24742724..24745263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068212909.1XP_068069010.1  swi5-dependent recombination DNA repair protein 1 homolog isoform X1