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galntl6 polypeptide N-acetylgalactosaminyltransferase like 6 [ Danio rerio (zebrafish) ]

Gene ID: 568915, updated on 27-Mar-2024

Summary

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Official Symbol
galntl6provided by ZNC
Official Full Name
polypeptide N-acetylgalactosaminyltransferase like 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-090312-115
See related
Ensembl:ENSDARG00000040048 AllianceGenome:ZFIN:ZDB-GENE-090312-115
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-15e22.3
Summary
Predicted to enable carbohydrate binding activity and hexosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Orthologous to human GALNTL6 (polypeptide N-acetylgalactosaminyltransferase like 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See galntl6 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (37752277..38131819)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (37033096..37412641)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-13d11.1 Neighboring gene si:dkeyp-13d11.2 Neighboring gene uncharacterized LOC101883643 Neighboring gene UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 Neighboring gene high mobility group box 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A novel inducible mutagenesis screen enables to isolate and clone both embryonic and adult zebrafish mutants. Ma Z, et al. Sci Rep, 2017 Sep 4. PMID 28871129, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables polypeptide N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
polypeptide N-acetylgalactosaminyltransferase-like 6
NP_001139074.1
XP_005160048.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145602.1 → NP_001139074.1  polypeptide N-acetylgalactosaminyltransferase-like 6

    See identical proteins and their annotated locations for NP_001139074.1

    Status: PROVISIONAL

    Source sequence(s)
    BX927375, CR391923, CT583668, CU462871
    UniProtKB/TrEMBL
    A0A8M1NTE2, B8A6C4
    Related
    ENSDARP00000150300.1, ENSDART00000189756.1
    Conserved Domains (4) summary
    cd02510
    Location:142 → 437
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:455 → 583
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:453 → 581
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    pfam10111
    Location:142 → 404
    Glyco_tranf_2_2; Glycosyltransferase like family 2

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    37752277..38131819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159991.4 → XP_005160048.1  polypeptide N-acetylgalactosaminyltransferase-like 6 isoform X1

    See identical proteins and their annotated locations for XP_005160048.1

    UniProtKB/TrEMBL
    A0A8M1NTE2, B8A6C4
    Related
    ENSDARP00000119502.1, ENSDART00000139448.3
    Conserved Domains (4) summary
    cd02510
    Location:142 → 437
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    cd00161
    Location:455 → 583
    RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
    pfam00652
    Location:453 → 581
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    pfam10111
    Location:142 → 404
    Glyco_tranf_2_2; Glycosyltransferase like family 2
Nucleotide Protein
Heading Accession and Version

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