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bag5 BCL2 associated athanogene 5 [ Danio rerio (zebrafish) ]

Gene ID: 569580, updated on 28-Oct-2024

Summary

Official Symbol
bag5provided by ZNC
Official Full Name
BCL2 associated athanogene 5provided by ZNC
Primary source
ZFIN:ZDB-GENE-050913-58
See related
Ensembl:ENSDARG00000017316 AllianceGenome:ZFIN:ZDB-GENE-050913-58
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:114117
Summary
Predicted to enable adenyl-nucleotide exchange factor activity and protein-folding chaperone binding activity. Predicted to be involved in negative regulation of protein ubiquitination; protein stabilization; and regulation of inclusion body assembly. Predicted to be active in cytosol; membrane; and nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2F. Orthologous to human BAG5 (BAG cochaperone 5). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See bag5 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (15757017..15799243, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (15631010..15668250, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene MAP/microtubule affinity-regulating kinase 3a Neighboring gene creatine kinase, brain a Neighboring gene tRNA methyltransferase 61A Neighboring gene cytochrome c oxidase assembly factor 8 Neighboring gene si:ch211-57f7.7 Neighboring gene kinesin light chain 1a Neighboring gene uncharacterized LOC101883107

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC114117

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables adenyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein-folding chaperone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in negative regulation of protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein stabilization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of inclusion body assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
BAG family molecular chaperone regulator 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034183.2NP_001029355.2  BAG family molecular chaperone regulator 5 isoform 1

    Status: VALIDATED

    Source sequence(s)
    BX569782
    UniProtKB/TrEMBL
    A0A8M9Q9W2, B8A5N0
    Related
    ENSDARP00000112636.1, ENSDART00000145914.3
  2. NM_001431071.1NP_001418000.1  BAG family molecular chaperone regulator 5 isoform 2

    Status: VALIDATED

    Source sequence(s)
    BX569782
    Related
    ENSDARP00000111840.1, ENSDART00000124688.3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    15757017..15799243 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)