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pdik1l PDLIM1 interacting kinase 1 like [ Danio rerio (zebrafish) ]

Gene ID: 569665, updated on 2-Nov-2024

Summary

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Official Symbol
pdik1lprovided by ZNC
Official Full Name
PDLIM1 interacting kinase 1 likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-051113-236
See related
Ensembl:ENSDARG00000056509 AllianceGenome:ZFIN:ZDB-GENE-051113-236
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fc95a02; zgc:123209
Summary
Predicted to enable eukaryotic translation initiation factor 2alpha kinase activity. Predicted to be involved in regulation of translational initiation. Predicted to act upstream of or within protein phosphorylation and regulation of autophagy. Predicted to be active in cytoplasm and nucleus. Orthologous to human PDIK1L (PDLIM1 interacting kinase 1 like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See pdik1l in Genome Data Viewer
Location:
chromosome: 19
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (15485556..15517398)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (15581194..15605441)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene finTRIM family, member 55 Neighboring gene lin-28 homolog Ab Neighboring gene protein phosphatase 1, regulatory subunit 8a Neighboring gene forkhead box O6 b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates. Goyal P, et al. PLoS One, 2009 Sep 16. PMID 19756140, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC123209

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables eukaryotic translation initiation factor 2alpha kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of autophagy IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine/threonine-protein kinase pdik1l
NP_001032789.2
XP_021323801.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037700.2 → NP_001032789.2  serine/threonine-protein kinase pdik1l

    Status: VALIDATED

    Source sequence(s)
    BC108040, CR936906, EG569238, EH552212
    UniProtKB/Swiss-Prot
    Q32PP3
    UniProtKB/TrEMBL
    A0A8M9PNI0, A5WV55
    Related
    ENSDARP00000073471.4, ENSDART00000079014.5
    Conserved Domains (1) summary
    cd13977
    Location:7 → 331
    STKc_PDIK1L; Catalytic domain of the Serine/Threonine kinase, PDLIM1 interacting kinase 1 like

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    15485556..15517398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021468126.2 → XP_021323801.1  serine/threonine-protein kinase pdik1l isoform X1

    UniProtKB/Swiss-Prot
    Q32PP3
    UniProtKB/TrEMBL
    A0A8M9PNI0, A5WV55
    Related
    ENSDARP00000147587.1, ENSDART00000182797.1
    Conserved Domains (1) summary
    cd13977
    Location:7 → 331
    STKc_PDIK1L; Catalytic domain of the Serine/Threonine kinase, PDLIM1 interacting kinase 1 like
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q32PP3.1 GenPept UniProtKB/Swiss-Prot:Q32PP3

Gene LinkOut

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