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cacng2b calcium channel, voltage-dependent, gamma subunit 2b [ Danio rerio (zebrafish) ]

Gene ID: 569855, updated on 2-Nov-2024

Summary

Official Symbol
cacng2bprovided by ZNC
Official Full Name
calcium channel, voltage-dependent, gamma subunit 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-090624-3
See related
Ensembl:ENSDARG00000102376 AllianceGenome:ZFIN:ZDB-GENE-090624-3
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable channel regulator activity and voltage-gated calcium channel activity. Predicted to be involved in several processes, including neurotransmitter receptor transport, postsynaptic endosome to lysosome; positive regulation of glutamatergic synaptic transmission; and postsynaptic neurotransmitter receptor diffusion trapping. Predicted to act upstream of or within calcium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in postsynaptic density membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 10. Orthologous to human CACNG2 (calcium voltage-gated channel auxiliary subunit gamma 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See cacng2b in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_003334443.1 (312..11581)
105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003334443.1 (312..11581)

NW_003334443.1Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 27 homolog (Chlamydomonas) Neighboring gene synaptogyrin 1b

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium channel activity  
enables channel regulator activity  
enables voltage-gated calcium channel activity  
Component Evidence Code Pubs
part_of AMPA glutamate receptor complex  
located_in membrane  
part_of monoatomic ion channel complex  
is_active_in postsynaptic density membrane  

General protein information

Preferred Names
calcium channel, voltage-dependent, gamma subunit 2b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199730.2NP_001186659.1  calcium channel, voltage-dependent, gamma subunit 2b

    Status: VALIDATED

    Source sequence(s)
    CABZ01090724, CABZ01090726
    UniProtKB/TrEMBL
    A0A0R4INZ4, A0A8M1NVJ4
    Related
    ENSDARP00000136308.1, ENSDART00000170434.1
    Conserved Domains (1) summary
    pfam00822
    Location:6197
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NW_003334443.1 Reference GRCz11 Primary Assembly

    Range
    312..11581
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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