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btr25 bloodthirsty-related gene family, member 25 [ Danio rerio (zebrafish) ]

Gene ID: 571141, updated on 28-Oct-2024

Summary

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Official Symbol
btr25provided by ZNC
Official Full Name
bloodthirsty-related gene family, member 25provided by ZNC
Primary source
ZFIN:ZDB-GENE-070705-377
See related
Ensembl:ENSDARG00000102018 AllianceGenome:ZFIN:ZDB-GENE-070705-377
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-218f9.5
Summary
Predicted to enable zinc ion binding activity. Predicted to be located in cytoplasm. Orthologous to several human genes including TRIM11 (tripartite motif containing 11); TRIM17 (tripartite motif containing 17); and TRIM39 (tripartite motif containing 39). [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See btr25 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (4059181..4065406)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (4128345..4134585)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene bloodthirsty-related gene family, member 23 Neighboring gene bloodthirsty-related gene family, member 24 Neighboring gene bloodthirsty-related gene family, member 26 Neighboring gene zgc:173581

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish. van der Aa LM, et al. BMC Biol, 2009 Feb 5. PMID 19196451, Free PMC Article
  2. Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish. Boudinot P, et al. PLoS One, 2011. PMID 21789205, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC173581

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
bloodthirsty-related gene family, member 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100041.2 → NP_001093511.1  bloodthirsty-related gene family, member 25 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CU861574
    Related
    ENSDARP00000135544.1, ENSDART00000161804.2
    Conserved Domains (7) summary
    COG0419
    Location:196 → 362
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd13733
    Location:375 → 548
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
    cd00162
    Location:38 → 77
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cd19769
    Location:164 → 208
    Bbox2_TRIM16-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM16, TRIM29, TRIM47 and similar proteins
    pfam05605
    Location:70 → 119
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    cl00034
    Location:113 → 160
    Bbox_SF; B-box-type zinc finger superfamily
    cl17238
    Location:35 → 78
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

  2. NM_001386812.1 → NP_001373741.1  bloodthirsty-related gene family, member 25 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CU861574
    UniProtKB/TrEMBL
    A0A8M2BL07, A9JSZ8
    Related
    ENSDARP00000130844.1, ENSDART00000172424.2
    Conserved Domains (7) summary
    COG0419
    Location:196 → 371
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd13733
    Location:378 → 551
    SPRY_PRY_C-I_1; PRY/SPRY domain in tripartite motif-containing (TRIM) proteins, including TRIM5, TRIM6, TRIM7, TRIM10, TRIM11, TRIM17, TRIM20, TRIM21, TRIM27, TRIM35, TRIM38, TRIM41, TRIM50, TRIM58, TRIM60, TRIM62, TRIM69, TRIM72, NF7 and bloodthirsty
    cd00162
    Location:38 → 77
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cd19769
    Location:164 → 208
    Bbox2_TRIM16-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM16, TRIM29, TRIM47 and similar proteins
    pfam05605
    Location:70 → 119
    zf-Di19; Drought induced 19 protein (Di19), zinc-binding
    cl00034
    Location:113 → 160
    Bbox_SF; B-box-type zinc finger superfamily
    cl17238
    Location:35 → 78
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    4059181..4065406
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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