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dap1b death associated protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 58094, updated on 18-Sep-2024

Summary

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Official Symbol
dap1bprovided by ZNC
Official Full Name
death associated protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-000511-4
See related
Ensembl:ENSDARG00000086842 AllianceGenome:ZFIN:ZDB-GENE-000511-4
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb369; hm:zeh0189; zgc:136540
Summary
Predicted to enable death domain binding activity. Predicted to be involved in apoptotic signaling pathway; cellular response to amino acid starvation; and negative regulation of autophagy. Is expressed in several structures, including central nervous system; hatching gland; hypochord; neural tube; and pronephric duct. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See dap1b in Genome Data Viewer
Location:
chromosome: 9
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (52378481..52403754, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (52836297..52864215, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496509 Neighboring gene bromodomain adjacent to zinc finger domain protein 2B Neighboring gene tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1b Neighboring gene uncharacterized LOC137496510 Neighboring gene death-associated protein-like 1 homolog Neighboring gene NME/NM23 family member 9 Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 Neighboring gene membrane associated ring-CH-type finger 4b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A molecular network of conserved factors keeps ribosomes dormant in the egg. Leesch F, et al. Nature, 2023 Jan. PMID 36653451, Free PMC Article
  2. Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. Huo X, et al. Sci Rep, 2019 Feb 6. PMID 30728369, Free PMC Article
  3. Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and mammalian lung. Zheng W, et al. PLoS One, 2011. PMID 21887364, Free PMC Article
  4. Identification, characterization, and mapping of expressed sequence tags from an embryonic zebrafish heart cDNA library. Ton C, et al. Genome Res, 2000 Dec. PMID 11116087, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC136540

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ribosome binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables translation initiation factor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables translation repressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to amino acid starvation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of autophagy IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome hibernation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosome hibernation IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
death-associated protein-like 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131573.2 → NP_571648.1  death-associated protein-like 1 homolog

    See identical proteins and their annotated locations for NP_571648.1

    Status: PROVISIONAL

    Source sequence(s)
    BC115168
    UniProtKB/Swiss-Prot
    A0A0R4IYW0, Q1RM22, Q9I9N0
    Related
    ENSDARP00000141912.1, ENSDART00000171721.2
    Conserved Domains (1) summary
    pfam15228
    Location:14 → 108
    DAP; Death-associated protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    52378481..52403754 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017357715.3 → XP_017213204.1  death-associated protein-like 1 homolog isoform X1

    UniProtKB/Swiss-Prot
    A0A0R4IYW0, Q1RM22, Q9I9N0
    Conserved Domains (1) summary
    pfam15228
    Location:14 → 108
    DAP; Death-associated protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I9N0.1 GenPept UniProtKB/Swiss-Prot:Q9I9N0

Gene LinkOut

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