mylz3 myosin, light polypeptide 3, skeletal muscle [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mylz3provided by ZNC
Official Full Name: myosin, light polypeptide 3, skeletal muscleprovided by ZNC
Primary source: ZFIN:ZDB-GENE-000322-6
See related: Ensembl:ENSDARG00000017441 AllianceGenome:ZFIN:ZDB-GENE-000322-6
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: mlc3; zeh0637; zf-e478; hm:zeh0637; ns:zf-e478; wu:fc33c02; zgc:109832
Summary: Predicted to enable calcium ion binding activity. Is expressed in musculature system; pectoral fin; and somite. Orthologous to human MYL1 (myosin light chain 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (7546345..7554360)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (6862914..6870925)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fb18e06.y1 (e-PCR)
- UniSTS:190249

AA566393 (e-PCR)
- UniSTS:206901

fc33c02.x1 (e-PCR)
- UniSTS:188007

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in contractile muscle fiber	IBA Inferred from Biological aspect of Ancestor more info
part_of myosin II complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: myosin, light polypeptide 3, skeletal muscle

Names: fast skeletal myosin light chain 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131619.3 → NP_571694.1 myosin, light polypeptide 3, skeletal muscle

See identical proteins and their annotated locations for NP_571694.1

Status: VALIDATED

Source sequence(s)

BC092705, CT998565

UniProtKB/TrEMBL

B2GPC1, F6P165, Q9I8U7

Related

ENSDARP00000018197.7, ENSDART00000015732.8

Conserved Domains (3) summary

PTZ00184
Location:1 → 150

PTZ00184; calmodulin; Provisional

cd00051
Location:94 → 146

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

cl08302
Location:12 → 76

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...