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pdp2 putative pyruvate dehydrogenase phosphatase isoenzyme 2 [ Danio rerio (zebrafish) ]

Gene ID: 58149, updated on 28-Oct-2024

Summary

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Official Symbol
pdp2provided by ZNC
Official Full Name
putative pyruvate dehydrogenase phosphatase isoenzyme 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-000921-2
See related
Ensembl:ENSDARG00000058571 AllianceGenome:ZFIN:ZDB-GENE-000921-2
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within protein dephosphorylation. Predicted to be active in mitochondrion. Orthologous to human PDP2 (pyruvate dehydrogenase phosphatase catalytic subunit 2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
all
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Genomic context

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See pdp2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (7452765..7456378, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (7493874..7497443, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene si:dkey-30c15.13 Neighboring gene si:dkey-30c15.12 Neighboring gene anillin, actin binding protein 2 Neighboring gene telomere repeat binding bouquet formation protein 1 Neighboring gene si:dkey-238c7.16 Neighboring gene neuropilin (NRP) and tolloid (TLL)-like 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC123270

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables cation binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial
NP_571700.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131625.2 → NP_571700.2  pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    BX470218
    Related
    ENSDARP00000075900.3, ENSDART00000081459.3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    7452765..7456378 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395003.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    98353..101965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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