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arfgap2 ADP-ribosylation factor GTPase activating protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 641490, updated on 28-Oct-2024

Summary

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Official Symbol
arfgap2provided by ZNC
Official Full Name
ADP-ribosylation factor GTPase activating protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-051120-177
See related
Ensembl:ENSDARG00000067601 AllianceGenome:ZFIN:ZDB-GENE-051120-177
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7148924; zgc:123303
Summary
Predicted to enable GTPase activator activity. Predicted to be involved in COPI coating of Golgi vesicle. Predicted to be located in Golgi membrane. Orthologous to human ARFGAP2 (ADP ribosylation factor GTPase activating protein 2). [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
human mouse all
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Genomic context

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See arfgap2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (44849852..44877073)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (44856361..44883619)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 118 member B Neighboring gene SRP receptor subunit alpha Neighboring gene si:ch211-71n6.4 Neighboring gene peroxisomal biogenesis factor 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC123303

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in COPI coating of Golgi vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ADP-ribosylation factor GTPase-activating protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037430.1 → NP_001032507.1  ADP-ribosylation factor GTPase-activating protein 2

    See identical proteins and their annotated locations for NP_001032507.1

    Status: PROVISIONAL

    Source sequence(s)
    BC108014
    UniProtKB/TrEMBL
    Q32PR4
    Related
    ENSDARP00000088098.3, ENSDART00000097328.5
    Conserved Domains (3) summary
    PLN03114
    Location:1 → 483
    PLN03114; ADP-ribosylation factor GTPase-activating protein AGD10; Provisional
    pfam01412
    Location:13 → 117
    ArfGap; Putative GTPase activating protein for Arf
    pfam12329
    Location:255 → 316
    TMF_DNA_bd; TATA element modulatory factor 1 DNA binding

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    44849852..44877073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159248.4 → XP_005159305.1  ADP-ribosylation factor GTPase-activating protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2B5S0
    Conserved Domains (3) summary
    PLN03114
    Location:1 → 498
    PLN03114; ADP-ribosylation factor GTPase-activating protein AGD10; Provisional
    pfam01412
    Location:13 → 117
    ArfGap; Putative GTPase activating protein for Arf
    pfam12329
    Location:270 → 331
    TMF_DNA_bd; TATA element modulatory factor 1 DNA binding
Nucleotide Protein Strain
Heading Accession and Version

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