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inka1a inka box actin regulator 1a [ Danio rerio (zebrafish) ]

Gene ID: 692272, updated on 2-Nov-2024

Summary

Official Symbol
inka1aprovided by ZNC
Official Full Name
inka box actin regulator 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060512-186
See related
Ensembl:ENSDARG00000070360 AllianceGenome:ZFIN:ZDB-GENE-060512-186
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fam212aa; sb:cb528; wu:fk96h10; zgc:136369; zgc:158531
Summary
Predicted to enable protein kinase binding activity and protein serine/threonine kinase inhibitor activity. Acts upstream of or within cartilage condensation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including axis; digestive system; nervous system; neural crest; and presumptive structure. Orthologous to human INKA1 (inka box actin regulator 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See inka1a in Genome Data Viewer
Location:
chromosome: 11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (35050262..35056607)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (34788269..34794614)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 38 member 3a Neighboring gene guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a Neighboring gene uncharacterized LOC137496719 Neighboring gene uncharacterized LOC137496720 Neighboring gene TRAF-interacting protein

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC158531

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine kinase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase inhibitor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cartilage condensation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cartilage development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
PAK4-inhibitor inka1
Names
family with sequence similarity 212, member Aa
inca1
induced in neural crest by AP2, 1a
induced in neural crest by AP2-alpha protein 1
protein FAM212A
zinca1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079988.1NP_001073457.1  PAK4-inhibitor inka1

    See identical proteins and their annotated locations for NP_001073457.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129272
    UniProtKB/Swiss-Prot
    A1L1Y9, F1QR98, Q1JQ16, Q503M7
    Related
    ENSDARP00000105046.2, ENSDART00000124800.3
    Conserved Domains (1) summary
    pfam15342
    Location:163202
    FAM212; FAM212 family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    35050262..35056607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)