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Ubqln5 ubiquilin 5 [ Mus musculus (house mouse) ]

Gene ID: 70980, updated on 28-Oct-2024

Summary

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Official Symbol
Ubqln5provided by MGI
Official Full Name
ubiquilin 5provided by MGI
Primary source
MGI:MGI:1918230
See related
Ensembl:ENSMUSG00000055643 AllianceGenome:MGI:1918230
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4931431F19Rik
Summary
Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Located in mitochondrion. Is expressed in olfactory epithelium. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

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See Ubqln5 in Genome Data Viewer
Location:
7 E3; 7 54.85 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (103777120..103779030, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (104127913..104129823, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 51 subfamily A member 24 Neighboring gene olfactory receptor family 52 subfamily D member 1 Neighboring gene STARR-seq mESC enhancer starr_19730 Neighboring gene ubiquilin 3 Neighboring gene ubiquilin-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The ubiquilin gene family: evolutionary patterns and functional insights. Marín I. BMC Evol Biol, 2014 Mar 28. PMID 24674348, Free PMC Article
  2. CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice†. Lu Y, et al. Biol Reprod, 2019 Aug 1. PMID 31201419, Free PMC Article
  3. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Mootha VK, et al. Cell, 2003 Nov 26. PMID 14651853
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables polyubiquitin modification-dependent protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
ubiquilin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027634.1 → NP_081910.1  ubiquilin-3

    See identical proteins and their annotated locations for NP_081910.1

    Status: VALIDATED

    Source sequence(s)
    AK016497
    Consensus CDS
    CCDS52341.1
    UniProtKB/TrEMBL
    Q9D4I8
    Related
    ENSMUSP00000062054.5, ENSMUST00000053743.6
    Conserved Domains (3) summary
    smart00213
    Location:24 → 94
    UBQ; Ubiquitin homologues
    cd14399
    Location:467 → 506
    UBA_PLICs; UBA domain of eukaryotic protein linking integrin-associated protein (IAP, also known as CD47) with cytoskeleton (PLIC) proteins
    cl00155
    Location:24 → 94
    UBQ; Ubiquitin-like proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    103777120..103779030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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