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tmem178a transmembrane protein 178a [ Danio rerio (zebrafish) ]

Gene ID: 767702, updated on 2-Nov-2024

Summary

Official Symbol
tmem178aprovided by ZNC
Official Full Name
transmembrane protein 178aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-756
See related
Ensembl:ENSDARG00000020758 AllianceGenome:ZFIN:ZDB-GENE-060929-756
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tmem178; zgc:153181
Summary
Predicted to be involved in negative regulation of osteoclast differentiation and regulation of cytosolic calcium ion concentration. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in lateral line ganglion. Orthologous to human TMEM178A (transmembrane protein 178A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See tmem178a in Genome Data Viewer
Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (30513790..30531095)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (30266606..30283911)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 3a Neighboring gene uncharacterized LOC137496710 Neighboring gene peroxisomal trans-2-enoyl-CoA reductase Neighboring gene solute carrier family 8 member 1a Neighboring gene mal, T cell differentiation protein a, tandem duplicate 1 Neighboring gene mal, T cell differentiation protein a, tandem duplicate 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC153181

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in negative regulation of osteoclast differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of osteoclast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 178A
Names
transmembrane protein 178

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076640.1NP_001070108.1  transmembrane protein 178A precursor

    See identical proteins and their annotated locations for NP_001070108.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124270
    UniProtKB/Swiss-Prot
    Q08CE6
    Related
    ENSDARP00000027372.8, ENSDART00000008594.10
    Conserved Domains (1) summary
    cl21598
    Location:110276
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    30513790..30531095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)